We interview Professor Patrick Pauwels, head of the laboratory of molecular pathology and co-director of CORE, a joint oncology research platform with the University of Antwerp. We covered the potential of liquid biopsies, such as urine in the field of cancer research especially when tissue is an issue. It also highlights URODETECT, a collaborative project between CORE & Novosanis, which focuses on investigating urinary biomarkers for prostate and breast cancer using the Colli-Pee device.