If you experience any technical difficulties with this video or would like to make an accessibility-related request, please send a message to [email protected]. Evolutionary developmental biology now permits a richer synthesis. But no similar synthesis has occured for cultural evolution, where institutional, technological, and individual development are crucial. Earlier acquired forms tune receptivity, transform-ation, and transmission of later ideas and practices for individuals, deeply confounding heredity, development, and selection. But processes of generative entrenchment can yield an alternative "endogenetics" (endomemetics?), while culturally induced population structure molds development as multiple sequentially acquired skills generate a coordinate "exomemetics". Overlapping breeding populations in a "socio-ecological" network promise a richer evolutionary dynamics of cultural change than "memetics".