This week we discuss an amazing new technique developed by Dr Jakub Gemperle (@GemperleJakub), a Marie Curie Postdoctoral Research Fellow at the University of Manchester (@OfficialUoM). This technique uses 3 different inducible systems to allow on-demand control of endogenous genes, including being able to remove genes and then re-express them. A nice all in one package of techniques, great for rescue experiments!! We then also talk about Magnetogenetics where cells (and vesicles) can be moved around via magnets! As always we ask how this person found preprinting and we delve into the wonderful idea of permanent postdocs. Read the full preprint: https://www.biorxiv.org/content/10.1101/2021.12.03.471086v1.full Other links https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3001285 First Pig to Human heart transplant https://www.nature.com/articles/d41586-022-00111-9 This episode was produced by Emma Wilson and edited by John D Howard. If you enjoyed this show then hit that subscribe button and leave a review. If you love what we are trying to do then support us on Patreon https://www.patreon.com/preprintsinmotion where tiers start at as little as £1 a month! For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com.