The 7 Vials of Wrath from God... The seven angels to whom were given the seven plagues symbolized in the seven vials are now commanded to pour out their divine judgment upon the earth. The voice is undoubtedly the voice of God which is described as coming out of the Temple and as being a “great” voice (Gr., megale„s), a word which occurs frequently in this chapter. The word great is mentioned again in connection with the great voice (v. 17), great heat (v. 9), the great river Euphrates (v. 12), that great day of God Almighty (v. 14), a great earthquake, “so mighty an earthquake, and so great” (v. 18), the great city (v. 19), great Babylon (v. 19), a great hail (v. 21), and the “exceeding great” plague (v. 21). As J. B. Smith expresses it, “This is the great chapter of the Bible.