The news is full of stories about monkeypox, the recent changes to COVID-19 guidance, and the return of polio cases. What do clinicians need to know? Contemporary Pediatrics sat down with its editor-in-chief, Tina Q. Tan, MD, FAAP, FIDSA, FPIDS, to discuss the what families can do to prevent polio, the most current information on monkeypox in pediatrics, and the new guidance from the Centers for Disease Control and Prevention on COVID-19.