Both human and mouse progenitor cells with the alterations struggle to become neurons and instead express genes that are typically active only in muscle or the heart. The post Autism-linked MYT1L mutations prompt ‘identity crisis’ in budding brain cells appeared first on Spectrum | Autism...

The approach removes methyl tags from the gene and shields it from other silencing factors without changing the gene itself, raising hopes for a new treatment. The post Epigenome edits unmute MECP2 in Rett-like neurons appeared first on Spectrum | Autism Research News.