On this episode of Sports Science Dudes, Dr. Chen shares how Radicle Science is using AI to transform clinical trials. This method not only garners authentic data but also reflects a true picture of how wellness products perform in the chaos of daily life. Timeline: 2:00 The process of how Radicle Science works 4:45 How do research subjects respond if an investigator is not present? 10:19 Adherence in these studies 11:39 The placebo effect 12:33 If you tell someone they are getting a placebo, they’ll still improve if you tell them it will help them 15:44 What’s the latest on CBD? Need a 100 mg dose or higher 20:30 Crowdsourcing as part of running a study 23:46 Who is the PI using the Radicle Science model? The data is owned by the client 26:40 What are the main endpoints that can be done by Radicle Science? Cost is 100k for a trial with a sample of 500 30:12 Radicle Science may serve as a good model for very active adults or elite athletes (e.g., sleep quality) 33:35 Longevity – Dr Chen’s philosophy 40:16 Evolutionary reasons – humans didn’t have many glucose spikes 41:26 Dr Chen’s way of making rice!  Dr. Jeff Chen, MD, MBA is an impact entrepreneur, executive, physician, and scientist on a mission to transform the health of our bodies and minds using non-pharmaceutical products. He is co-founder/CEO of Radicle Science, an AI-driven healthtech B-Corp providing history's first Proof-as-a-Service solution for wellness products to easily prove their true effects at unprecedented affordability, speed, and scale.  Radicle Science was named by KPMG as one of the Top Ten US “Tech Innovators” of 2022 and by Fast Company as a “World Changing Idea”.  Dr. Jeff gave a MainStage Talk on Radicle Science at TED 2023.   Previously he was the founder and Executive Director of a UCLA research center where he led clinical trials on natural products.  Dr. Jeff has been interviewed by outlets including CNN, Forbes, Wall Street Journal, TIME, NPR, Entrepreneur, Rolling Stone, NBC News, Financial Times, WebMD, Politico, Business Insider, SF Gate, VICE, Vogue and more for his expertise.  Following a BS at Cornell, Dr. Jeff earned his MD and MBA concurrently at UCLA. About the Show We cover all things related to sports science, nutrition, and performance. The Sports Science Dudes represent the opinions of the hosts and guests and are not the official opinions of the International Society of Sports Nutrition (ISSN), the Society for Sports Neuroscience, or Nova Southeastern University. The advice provided on this show should not be construed as medical advice and is purely an educational forum. Hosted by Jose Antonio, PhD Dr. Antonio is the co-founder and CEO of the International Society of Sports Nutrition and the co-founder of the Society for Sports Neuroscience, www.issn.net. Dr. Antonio has over 120 peer-reviewed publications and 16 books. He is a Professor at Nova Southeastern University, Davie, Florida in the Department of Health and Human Performance. Twitter: @JoseAntonioPhD Instagram: the_issn and supphd Co-host Anthony Ricci EdD Dr Ricci is an expert on Fight Sports and is currently an Assistant Professor at Nova Southeastern University in Davie Florida in the Department of Health and Human Performance. Instagram: sportpsy_sci_doc and fightshape_ricci