The 2022 Nobel Prize in Chemistry was awarded to Carolyn Bertozzi, Morten Meldal and K. Barry Sharpless for their development of click and bioorthogonal chemistry which are used by chemists around the world to track biological processes and produce pharmaceuticals. In this special episode of Stereo Chemistry, hosts Gina Vitale and Ariana Remmel delve into the science behind the prize and talk with organic chemist Antoni Riera to discuss the applications of the award-winning chemistry. C&EN contributor Mark Peplow also joins the Stereo Chemistry crew to talk about his conversation with Nobel Laureate Carolyn Bertozzi. Read more about this award-winning science in Mark Peplow's article about the 2022 Nobel Prize in Chemistry: https://cen.acs.org/people/nobel-prize/Click-and-biorthogonal-chemistry-win-2022-Nobel-Prize-in-Chemistry/100/web/2022/10  A transcription of this episode is available at https://cenm.ag/nobelpod22. CORRECTION: On Oct. 6, 2022, part of this episode was rerecorded to correct an error at 0:48 about when the 2022 Nobel Prize in Chemistry was announced. It was announced Oct. 5, not Oct. 6. The episode description was also updated to remove Heather Holt as copyeditor. She did not copyedit this episode. Credits Executive producer/host: Kerri Jansen Writer: Ariana Remmel, Gina Vitale Audio editor: Mark Feuer DiTusa Story editors: Jessica Marshall Production assistance: Mark Peplow, Krystal Vasquez Audience editor: Dorea I. Reeser Logo design: William A. Ludwig Episode artwork: Laura Morton (Bertozzi), University of Copenhagen (Meldal), Sandy Huffaker (Sharpless) Press conference recordings: Courtesy of ©The Nobel Foundation Music: “Rising Tide” by C.K. Martin.   Contact Stereo Chemistry: Tweet at us @cenmag or email [email protected].