Drs. Akshay Thomas and Priya Vakharia join to discuss the March 2023 issue of Retinal Physician, found online at http://www.retinalphysician.com. Topics covered include gene therapy and immunogenecity, applications in dry AMD, and optogenetics. Relevant Financial Disclosures: Dr. Sridhar has consulted for RegenxBio and Apellis in the past 2 years. You can claim CME credits for prior episodes via the AAO website. Visit https://www.aao.org/browse-multimedia?filter=Audi