Key Terms: Thrombolysis, endovascular therapy, Hosts: Ryan Muir, Houman Khosravani Summary: In this episode the hosts discuss the future of stroke by exploring and proposing novel applied modern concepts of endovascular and thrombolytic therapies to innovative and creative ideas for the future. Endovascular therapy for distal vessels is discussed Improving geographic access to endovascular therapy (especially for wide spread countries like Canada) The role of the NIHSS score in the acute assessment of stroke in the future and the increasing reliance on imaging parameters to guide decision making The future of thrombolysis The future of neuroimaging: Evolving understanding of ASPECTS and MRI Brain (Solid state MRI in acute stroke assessments), and potential role for focused ultrasound Neuroprotection and extending time-windows