In this latest episode of our Research Corner series, Dr. Hill sits down with PGY-3 Adam Gottula, MD and Amanda Peck, PharmD to discuss their recently published case report describing the use of dexmedetomidine for the management of acute intrathecal baclofen withdrawal. The discussion encompasses the mechanisms of action of baclofen, dexmedetomidine, and how dexmedetomidine might be useful in the management of these complex patients.