In this episode, we navigate the post-April Fools' day landscape, highlighting the latest in tech and AI. Chrome introduces AI-enhanced themes and tab customizations, while Dalle 3 brings advanced in-painting capabilities, sparking discussions about its practical use in the artistic community. We spotlight creators like Dustinhollywood, who impresses with his AI-generated sci-fi film "The Last Artist," and Dave Clark, aka Diesol, for his short film "Edgehunter." On the job front, we share a lead for front-end engineers at Anduril, aiming to expand their generative AI team. We delve into significant industry shifts with Sam Altman stepping down from OpenAI's VC fund, steering towards a broader collaboration with Microsoft, and Amazon revising its checkout technology in Fresh stores, replacing "Just Walk Out" with Dash Carts for a more transparent shopping experience. These changes reflect the ongoing evolution and skepticism in AI's practical applications. Wrapping up, we explore Stanford Medicine's breakthrough with SyntheMol, an AI model creating new drugs against antibiotic-resistant bacteria, marking a significant step in healthcare innovation.