Take yer stinkin’ proteins off me you damn, dirty microbe! This time Harland asks the question: Is there any way for us provincial primates—with all our adaptations for dealing with smaller scales—to address planetary-sized problems? We discuss from there topics ranging along the lines of logistics, motivational strategies, and hopelessness and helplessness. Unfortunately, we are the mercy of this pan-troglo-demic. What else are we at the mercy of that is of our own making? -Dawds