In this installment of The Empowering Neurologist we are privileged to welcome Dr. Nathan Bryan, a trailblazer in the realm of biomedical research, with a specific focus on the life-sustaining molecule, nitric oxide.  As a globally recognized pioneer in nitric oxide biochemistry and physiology, Dr. Bryan’s contributions have significantly shifted our understanding of the role of nitric oxide in overall human health. I had the privilege of attending a lecture given by Dr. Bryan recently and learned that he is a tenacious advocate for understanding nitric oxide not as a mere molecule, but as a vital bioactive substance with a profound influence on numerous physiological processes. His extensive research has elucidated nitric oxide's pivotal roles in areas like maintaining vascular health, bolstering the immune system, and regulating the cardiovascular system. These insights have been instrumental in revolutionizing therapeutic strategies and disease management methods. In a world beset by increasing health challenges, understanding the critical role of nitric oxide is paramount. This molecule is the very fulcrum of our well-being, influencing how cells communicate and interact, determining disease resistance, and even dictating our longevity. Dr. Bryan's invaluable work unveils the importance of maintaining nitric oxide balance for optimum health and wellbeing. And interestingly, the nitric oxide story fully dovetails with our work in the area of uric acid as we discuss. I’m certain you will be fascinated by this interview as we do a deep dive into the world of nitric oxide with Dr. Bryan, whose pioneering work continues to enlighten us on the intricate mechanisms that drive human health. This conversation promises to challenge preconceived notions, inspire new health perspectives, and fundamentally reshape how we approach wellness in the 21st century.   Timestamps   0:00 Intro 3:14 Nitric Oxide 5:29 Measuring Nitric Oxide “interestingly” 8:36 Oral Health and Nitric Oxide 15:02 Acid Blocking Drugs 18:00 Dietary Sources of Nitrates 19:55 Oxygen Availability 23:14 MTFHR 27:46 Age and Nitric Oxide 30:42 Viagra 35:46 Wound Healing 43:27 Latest Findings 46:27 Nathan’s Book Release 48:23 Conclusion   ====   Dr. Bryan earned his undergraduate Bachelor of Science degree in Biochemistry from the University of Texas at Austin and his doctoral degree from Louisiana State University School of Medicine in Shreveport where he was the recipient of the Dean’s Award for Excellence in Research.  He pursued his post-doctoral training as a Kirschstein Fellow at Boston University School of Medicine in the Whitaker Cardiovascular Institute.  After a two year post-doctoral fellowship, in 2006 Dr. Bryan was recruited to join faculty at the University of Texas Health Science Center at Houston by Ferid Murad, M.D., Ph.D., 1998 Nobel Laureate in Medicine or Physiology.  Dr. Bryan has been involved in nitric oxide research for the past 20 years and has made many seminal discoveries in the field.  His many seminal discoveries have resulted dozens of issued US and International patents and the product technology resulting from his discoveries and inventions has improved patient care worldwide.  Dr. Bryan is a successful entrepreneur and Founder of HumanN, Inc, Pneuma Nitric Oxide, LLC, Nitric Oxide Innovations, LLC and Bryan Nitriceuticals, LLC.  His product technology is responsible for hundreds of millions of product sales worldwide.  Most recently, Dr. Bryan serves as Founder and CEO of Nitric Oxide Innovations, LLC, a privately-held, clinical-stage biopharmaceutical company that is actively engaged in the discovery and development of nitric oxide based therapies.  Their lead drug candidate NOviricid is currently in phase 3 clinical trials for the treatment of COVID19 in African Americans and Hispanics.  Dr. Bryan is an international leader in molecular medicine and nitric oxide biochemistry.     w