Our podcasts about research are often are the most popular, so hopefully today’s will also deliver. Today’s topic explores another often-misunderstood condition Postural Tachycardia Syndrome or (POTS) as it often called - and its possible connection to celiac disease. This is a condition that presents with a variety of symptoms that can be difficult to diagnose – like chronic fatigue, lightheadedness, fainting, an uncomfortable, rapid increase in heartbeat when standing up, and a range of GI symptoms. POTS has even been referred to as the “invisible disease.” Today we want to discuss the gastrointestinal symptoms associated with this condition and its possible link with celiac disease.  We have a team of fantastic experts with us here in the studio to help us better understand POTS and the studies linking it to celiac disease. We have Dr. Jeffrey Moak, the director of electrophysiology and pacing in the department of cardiology at Children’s National Hospital and Dr. Jocelyn Silvester, the director of research for the Celiac Program at Boston Children’s Hospital. Studies referred to during the episode https://jnnp.bmj.com/content/jnnp/76/4/579.full.pdf https://pubmed.ncbi.nlm.nih.gov/25554987/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314490/ https://www.ahajournals.org/doi/10.1161/JAHA.119.013602 Thank you to the Global Autoimmune Institute for their ongoing support to make this podcast possible.