We are in the midst of a weight loss revolution, and it's not thanks to your local quack-doctor or health guru. Semaglutide, a glucagon like peptide-1 receptor (GLP-1) agonist, is approved by the FDA for weight loss and has been all over the mainstream and social media as a miracle drug that millions are turning to to shed excess weight. But where did this medicine come from and what is the science, and even the risks behind it? That is the topic for this episode of Health In Harlem. As always, we welcome your questions and comments and we hope that you learn from our program and the only thing we ask is that you share what you learn with anyone that will listen. Harlem (aka people of the World), take care of yourself. Frontiers in Endocrinology: The Discovery and Development of Liraglutide and Semaglutide https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474072/ Associated Press: New Guidance: Use Drugs, Surgery Early for Obesity in Kids https://apnews.com/article/obesity-kids-drugs-surgery-new-guidance-c48d5896114beea7eda31d7b8b25461d New England Journal of Medicine- Weight and Health https://www.nejm.org/doi/full/10.1056/NEJMp2214423?query=recirc_curatedRelated_article New England Journal of Medicine- When Weight Impacts Health https://www.nejm.org/doi/full/10.1056/NEJMp2215794?query=recirc_curatedRelated_article Pediatrics: Clinical Practice Guidelines for the Evaluation and Treatment of Children and Adolescents with Obesity https://publications.aap.org/pediatrics/article/151/2/e2022060640/190443/Clinical-Practice-Guideline-for-the-Evaluation-and?autologincheck=redirected The New York Times: Ozempic Can Cause Major Weight Loss. What Happens When You Stop Taking It? https://www.nytimes.com/2023/02/03/well/live/ozempic-wegovy-weight-loss.html