Generating scientific evidence is, although essential, just the first step. For clinical practice to be driven by evidence we must ensure that the knowledge is translated into policies that guide practice and are available for all. But how? The road from research to clinics is not a linear one, nor it is the same in every setting. Trials conducted in high-income countries can offer limited support to practice-changing in other contexts. So how do we go from evidence to implementation? Taissa Vila, Editor-in-Chief at The Lancet Regional Health - Americas, speaks with Ana Claudia de Souza, a stroke neurologist and trialist at Hospital Moinhos de Vento in Brazil about translating evidence to clinical practice in low- and middle-income settings. You can see all of our Spotlight content relating to research for health here: https://www.thelancet.com/lancet-200/research-for-health?dgcid=buzzsprout_tlv_podcast_lancet200_rfh Find out more about how The Lancet is marking its 200th anniversary with a series of important spotlights here: https://www.thelancet.com/lancet-200?dgcid=buzzsprout_tlv_podcast_lancet200_rfh Continue this conversation on social! Follow us today at... https://twitter.com/thelancet https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://linkedIn.com/company/the-lancet https://youtube.com/thelancettv