Episodes
Join the guys on a very special episode featuring Professor Carel le Roux. Carel is a physician working in St. Vincent’s Hospital in Dublin, he is also a Professor of experimental pathology at University College Dublin. His work and research are focused on the physiological role and pathological changes in appetite control, the impact of bariatric surgery on diabetes and concerns with increased mortality and morbidity associated with obesity and diabetes. During the conversation we discuss...
Published 03/23/22
In this episode Tom brags about his new tattoo and a habit of journaling. Evan brings us back to 2019 and tries to make sense of the origins of the COVID-19 pandemic while Tom explores the secrets of limb regeneration via a new paper which explores an animal model in which limb regeneration was achieved with promising results.
Published 03/10/22
In Episode 34 of the podcast, Tom discusses his aspirations to own a tooth necklace while the lads lament their nations' poor performance at the Winter Olympics. In his main story, Tom sets the story straight on the new HIV variant while Evan examines ketamine for acute suicidal ideation along with microdosing in anxiety treatment and what this could mean in the future of mental health treatment.
Published 02/24/22
On today's episode the guys discuss the new marketing methods of crypto.com, Tom examines a new early diagnostic test for lung cancer while Evan dives into the recent row between the British Medical Journal and Facebook who labelled one of their articles as misinformation, and what this could mean for the future of science articles on the site.
Published 02/10/22
Welcome to the first episode of 2022 where the lads have a quick recap of science over the festive period, including sex in the pandemic era and the 'Shkreli' awards. In his main story, Tom questions the claims of higher rates of myocarditis in vaccinated people versus individuals infected with SARS-CoV-2.
Published 01/27/22
Join us for our final episode of 2021 where Tom and Evan review the science of the past year. We remember the most exciting news stories, including mRNA breakthroughs and some of the weird and funny headlines, like, 'What animal would live in a communist society?'. We also make some predictions for science in 2022. So top your year off with some humour, discussion and education on The Sceptically Inclined Podcast!
Published 12/23/21
On today's episode, the lads debate a new pilot study being introduced by the UK government to sequence the genome of children at birth with Tom being pro while Evan takes an opposing position. Tom gives his thoughts on his recent Dan Brown book experience while Evan examines a new landmark case of "wrongful conception". So join us for some laughs, discussion and debate on the Sceptically Inclined Science Podcast
Published 12/09/21
In today's episode, Evan reassures Tom that lockdowns are still a good preventive measure against COVID-19 and sums up COP26 as an unfortunate failure. On a positive note, the booster vaccine against COVID-19 shows very promising results. Tom compares solid tissue biopsies and liquid biopsies - is one better than the other? Can we get rid of one? Tune in to find out!
Published 11/25/21
In this weeks episode we learn that not only does James Bond have amazing espionage skills but also an impenetrable immune system.    Tom celebrates the Phase II//III results for antiviral drug "Paxlovid" against SARS-COV-2 and dives into the events at COP26 while Evan evaluates the controversial approval of a new Alzheimer's drug, Aducanumab, and examines what the clinical trial results actually said.
Published 11/11/21
On today's episode we are joined by special guest Professor Han Brunner. Prof Brunner has worked on understanding the MAOA gene mutation, and how it leads to abnormal, unpredictable behaviour as well as uncontrolled violence. Learn about the science behind MAOA influence on brain development, the influence of maltreatment on behaviour and how MAOA status has influenced court cases previously in an exciting and insightful discussion.
Published 10/28/21
In this episode, Evan reviews the Nobel Prize winners in the scientific categories and the other science news including the malaria vaccine and a new sickle cell anemia treatment. In his main story, Tom discusses the X and Y chromosomes, X-inactivation and treatment options for chromosome inactivation.
Published 10/14/21
Join Evan and Tom as they welcome you back to a new season of The Sceptically Inclined Science Podcast. In this episode, the guys talk scientific YouTube comments, Tom covers interesting science headlines that you might have missed over the summer and Evan examines booster vaccines, waning immunity and full authorisation of the Pfizer-BioNTech Covid-19 vaccine. So join us for a new season of laughs, discussion and fun accessible science chat!
Published 09/30/21
Join the guys for the final episode of the season! Tom, Evan and John reflect on a whole year of non-stop podcasting. Along with nominating their favourite moments and guests, the guys discuss stories that didn't make the cut. From animals that Tom thinks he could manhandle, to Evan's crazy sleep-talking. So take a trip down memory lane with the lads as they conclude this season on a high and explicit note!
Published 07/01/21
On this episode we are joined by Professor Ivan Perry. Professor Perry is the Dean of the School of Public Health at University College Cork with particular expertise in cardiovascular disease, diabetes and self-harm. We discuss obesity in Ireland, his thoughts on the public health response to the Covid-19 pandemic in Ireland and the effect it has had on mental health. Enjoy!
Published 06/17/21
Join the guys for a special episode featuring Dr Alex Garanto. Alex is an Assistant Professor at Departments of Pediatrics and Human Genetics in Radboud University Medical Center. Alex has over a decade of experience working on oligonucleotides based therapies for inherited retinal diseases. Tom and Evan discuss with Alex the complexity of eye, the burden of inherited blindness on patients and the role of pharmaceutical companies in developing gene therapies. The guys also had the opportunity...
Published 06/03/21
Welcome to episode 21 where the lads discuss what it means to be a science influencer and using PubMed to feel better about themselves.in their main stories, Tom examines how some genetic diseases can evolve to provide an advantage in infectious diseases while Evan dives into COVID-19 vaccination in children and the difficulties in its implementation. All topped off with some discussion, humour and science news.
Published 05/20/21
In Episode 20, Tom discusses his disappointment with Assassins Creed and Evan ponders his new haircut choice. For the news headlines John discusses Neuralink's monkey brain pong, Tom examines the updated CDC mask guidelines and Evan investigates smell training.In the main news, Tom discusses his experience with pain and a new study that may help reduce this while Evan examines the pros and cons of a vaccine passport. So join us for some humour, discussion and science fun.
Published 05/06/21
Welcome to Episode 19 where we talk blood personalities, blood clots and vaccines. The guys try to decipher John's blood group based on his personality while in the headlines Evan discusses new findings in relation to Neanderthals.In their main stories, Evan has a deep dive into the recent troubles with the Oxford/AstraZeneca vaccine and Tom examines the potential of RNA technology in treating Multiple Sclerosis. So join us for humour, discussion and more.
Published 04/22/21
On this episode Evan and Tom talk coronavirus, concussion and blood products of the future.Tom reveals his awkward encounter while getting some sausage and talks about synthetic cells. Evan briefly examines the AstraZeneca vaccine and the the new WHO report on the origin of COVID-19.In their main stories Evan discusses a new diagnostic test for concussion while Tom wraps up his series on blood substitutes and potential future opportunities. All topped off with some discussion and humour.
Published 04/08/21
Join the guys for a very special episode featuring Professor Luke O'Neill. Luke is an immunologist, biochemist and author based in Trinity College Dublin. Tom and Evan discuss the work Luke is doing in his lab to combat COVID-19, his thoughts on the European pause of the AstraZeneca vaccine and the challenges of science communication in an era of misinformation. So join us for some great discussion and insights from one of Ireland's top research professors.
Published 03/25/21
Join the guys as Evan discusses getting his first vaccine dose and his urge to buy Microsoft products, Tom's hope to start LSD micro-dosing takes a step forward and John rejoins to relive the perseverance rover landing on Mars.For their main stories, Evan casts a sceptical eye on the hype of the microbiome while Tom gives us part one of his talk on blood transfusion and the possibility of using non-blood based products. All topped off with some discussion, humor and debate.
Published 03/11/21
Join us on Episode 15 where are joined by animal cognition researcher Dr Jim McGetrick. Jim is a Postdoctoral scientist, specialising in animal behaviour and higher cognition, primarily in dogs.The guys quiz Jim on all things animal related ranging from whether your dog can truly love you, to monogamy in birds and what your dog breed can really say about you. All topped off with some humour, discussion and hopefully you can leave with some cool facts about animal behavioural science. 
Published 02/25/21
On Episode 14 of the Sceptically Inclined Science Podcast the guys discuss an unorthodox method of swabbing for Covid-19 and they try out a new segment where they discuss David Attenborough, the "nature guy".For their main stories, Evan examines deep brain stimulation and how it is used in treating disease, along with Neuralink, while Tom discusses the male "pill", its use as a contraceptive and everyone's reaction to taking it.All topped off with some humour, discussion and fun.
Published 02/11/21
On Episode 13 of the Sceptically Inclined Science Podcast, the lads discuss Netherlands under curfew, moving away from WhatsApp and Michelle Obama becoming a Jedi.In the main discussion, Tom investigates a new peptide that may help in the treatment of COVID-19 while Evan examines asymptomatic transmission and whether it is a driver of cases or not.So join us for some discussion, laughs and news from the science world.
Published 01/28/21
On Episode 12 of the Sceptically Inclined Science Podcast the guys welcome you to the new year by talking about all things vaccine-related. Tom discusses recent anaphylactic reactions in some vaccine recipients and the molecular mechanisms of how the Pfizer/BioNTech and Moderna vaccines work.Evan examines vaccine trials, how they were carried out for the vaccines developed for SARS-COV-2 and casts his sceptical eye on the recent Pfizer/BioNTech data that had been released.
Published 01/14/21