In this episode, sponsored by Bio-Techne, Drs. Hans Clevers and Kai Kretschmar join the podcast to talk broadly about the role of adult stem cells in tissue maintenance and repair. Specifically, they will focus on the expression and function of Troy and stem cells in the development and homeostasis of the epidermis, the outermost layer of the skin, that functions as a protective mechanical and biological barrier against injuries, pathogens and the loss of heat and water. Guests Hans Clevers, MD, PhD, is group leader at the Hubrecht Institute for Developmental Biology and Stem Cell Research and at the Princess Máxima Center for Pediatric Oncology. He is also University Professor at the University Utrecht and Oncode Investigator. Both in the Netherlands.  Kai Kretzschmar, PhD, is junior group leader at the MSNZ University Hospital Würzburg, Germany  Host Martin Pera, PhD – Editor-in-Chief, Stem Cell Reports and The Jackson Laboratory Twitter: @martinperaJAX Supporting Documents Troy/Tnfrsf19 marks epidermal cells that govern interfollicular epidermal renewal and cornification About Stem Cell Reports Stem Cell Reports is the Open Access journal of the International Society for Stem Cell Research (ISSCR) for communicating basic discoveries in stem cell research, in addition to translational and clinical studies. Stem Cell Reports focuses on original research with conceptual or practical advances that are of broad interest to stem cell biologists and clinicians. Twitter: @StemCellReports About ISSCR With nearly 4,000 members from more than 65 countries, the International Society for Stem Cell Research is the preeminent global, cross-disciplinary, science-based organization dedicated to stem cell research and its translation to the clinic. The ISSCR mission is to promote excellence in stem cell science and applications to human health. Twitter: @ISSCR Acknowledgements ISSCR Staff Keith Alm, Chief Executive Officer Bethany Almon, Senior Manager of Integrated Marketing Yvonne Fisher, Managing Editor, Stem Cell Reports Kym Kilbourne, Director of Media and Strategic Communications Jack Mosher, Scientific Advisor Voice Work Ben Snitkoff Music @Konovalov