Nels and Vincent discuss an analysis of the drivers of evolution of SARS-CoV-2 during chronic infections, indicating that a tradeoff exists between antibody evasion and fitness. Hosts: Nels Elde and Vincent Racaniello Click arrow to play Download TWiEVO 79  (103 MB .mp3, 86 min) Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiEVO Links for this episode SARS-CoV-2 evolution during chronic infection (Nat Med) Letters read on TWiEVO 79 Time stamps by Jolene. Thanks! Science Picks Nels – NASA scientists say images from the Webb telescope nearly brought them to tears Vincent – FDA: Don’t rush a move to change the Covid-19 vaccine composition Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to [email protected]