In this enlightening episode, Natasha Vita-More, a luminary in the transhumanist movement and an advocate for human enhancement, shares her profound insights on nurturing both mental and physical well-being. As an innovator, professor, and Executive Director of Humanity+, Natasha brings a rich background in cryobiology, body-brain engineering, and her extensive academic pursuits, including a Ph.D. and two Masters, to the conversation. She delves into the importance of understanding and managing emotions, emphasizing the role of meditation, especially transcendental meditation, in achieving a balanced life. Natasha discusses the critical concept of neural plasticity, likening it to a sport that requires daily practice, and stresses the significance of a brain-healthy diet, interspersed with life's small pleasures. Her advice extends to learning new skills and embracing adult neurogenesis, highlighting the necessity of regular physical exercise for brain health. Drawing inspiration from David Eagleman, a renowned neuroscientist, she encourages listeners to challenge themselves and support those around them. This episode is not just a discussion on transhumanism and advanced general intelligence (AGI) but a guide to making each day count for personal health and happiness, ultimately leading to a kinder, more fulfilling life.