Today I am speaking with Carolina Reis Oliveira, OneSkin Co-Founder & CEO. We discuss the importance of addressing the root cause of skin aging and the role of senescent cells in the aging process. We also talk about the skin barrier and how it can become compromised. Carolina shares her thoughts on retinol and the importance of listening to your skin's reaction to products. OneSkin measures skin aging through the epigenetic signature of the skin. OneSkin has developed a peptide called OS1 that has been shown to reduce the age of the skin by 2.5 years in humans. The peptide works by reducing the load of senescent cells and promoting collagen production. OneSkin is constantly researching and developing new products to target skin aging and are exploring the potential of using their peptide for other inflammatory conditions. OneSkin believes in the importance of staying at the forefront of scientific research and innovation to provide the most effective products for skin aging. Save 15% off OneSkin with code KAYLACLICK HERE to SHOP! ABOUT CAROLINAFascinated with biology from a young age, Carolina knew she’d have a future in science. A fearless leader with a passion for longevity and living life to the fullest, she embarked on an ambitious goal — to delay the onset of age-related diseases by targeting aging itself. This led her to earn degrees in stem cell biology and tissue engineering, and a doctorate in immunology. Then, determined to translate her academic achievements into real-world impact, Carolina left her native Brazil for Silicon Valley, co-founding OneSkin in 2016. As Chief Executive Officer, Carolina and her team spearhead research and development, creating molecules that target cellular aging, including their pioneering innovation, the OS-01 peptide. Follow OneSkin on Instagram Chapters00:00 Carolina's Background and Interest in Skin Health 03:03 The Impact of Aging on Health and Disease 11:45 Targeting Senescent Cells for Reversing Damage 13:12 The Importance of the Skin Barrier 26:08 Investing in Long-Term Skin Health 30:00 Measuring Skin Aging and the Use of Devices 36:24 Sun Exposure and SPF Recommendations 40:12 The Age-Reversing Effects of OS1 Peptide 45:19 The Potency of the Eye Cream for Delicate Skin 48:28 Exploring the Potential of the Peptide for Inflammatory Conditions 50:48 Future Possibilities: Supplements and Injectables 52:37 Red Light Therapy and Personal Protocol 55:29 Staying at the Forefront of Scientific Research and Innovation 59:21 DISCLAIMER