In the final episode of the podcast I, Sal Daher, review important lessons I learned in seven years of interviews and decades of investing. In my voice and in the voice of my guests, I recapitulate the discoveries most salient to me and invite listeners to find their own nuggets in the sound archive which will remain available on Apple Podcasts and other platforms. AngelInvestBoston.com will have 250 episode pages with sound, notes, and in most cases, annotated transcripts. I’ll be...

Lessons Learned is a compilation of hard-won lessons in angel investing. They come from my podcast interviews over these seven years as well as from my three decades of angel investing. Hints on how to build your portfolio, how to eliminate sure losers and other practical advice will be offered in the voice of my guests and in my own voice. Sorry that the release of the episode is delayed until Friday 12/29 due to personal matters and this year's Christmas calendar. Thanks for listening.

Aging Fit Substack: Learn More   Repeat life science entrepreneur Tom Weldon is now taking on aging. He is commercializing a compound to extend health span developed at a prominent institution. Composed of substances generally considered as safe by the FDA, the formula has shown impressive results in mice and, to date, in one human, Tom himself. Intriguing chat with a dynamic founder.   Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and...

Aging Fit Substack: Learn More   Raul Rosa, artist, musician, and sound engineer, discusses his work with the Angel Invest Boston Podcast, some of his favorite interviews, and his own startup, Podspot.   Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and Richardson.   Highlights: Sal Daher Introduces Raul Rosa Raul's Favorite Interviews Fortified Bike Howard Stevenson PodSpot Wistia Piction Health Savran Technologies Advice to the Audience ...

Aging Fit Substack: Learn More   Life science board member and advisor Paul Hartung is back with wise tips on how to fund your biotech startup in these had times. Listen or read below.   Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and Richardson.   Highlights: Paul Hartung, Experienced Biotech Board Member & Advisor Paul Hartung Closed a Financing in the Midst of the Last Recession Seek Out the Right Grant Funding, Watch Expenses Pitch...

Aging Fit Substack: Learn More   In my fourth decade of angel investing, I’m happy with my investments but regret having put them in my IRAs. Here are pros and cons of having illiquid, operationally complex and hard-to-value assets in IRAs.   Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and Richardson.   Highlights: Investing in Startups via an IRA Can Be Burdensome, Here’s Why How I came to Have so Much of my Net Worth in my IRAs Thank You...

Aging Fit Substack: Learn More   Katharine Woodman-Maynard has for seven years created a gorgeous and enduring graphic manifestation of this podcast on the web. I am fortunate to have this gifted artist enhancing my work with her talent and wisdom. She returns to talk about her favorite interviews, to share her journey as a professional artist and to offer valuable advice for those starting out.   Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish...

Aging Fit Substack: Learn More   Ethan Pierce’s startup Adaptive Reader makes great literature accessible to kids not reading at grade level. Harnessing generative AI with sophisticated prompts and quality control by humans creates compelling texts based on the classics. Ethan and his co-founder even have a promising business model. Great chat!   Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and Richardson.   Highlights: Sal Daher Introduces...

Angel Scale Biotech: Learn More   Brian Denenberg is an angel investor, company advisor, and co-founder. Here, he discusses some of the companies he has been involved with, including Fairmarkit, Tive, and his work at Venture Lane Studio helping startups grow sales.   Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and Richardson.   Highlights: Sal Daher Introduces Brian Denenberg Fairmarkit How Fairmarkit Was Started Tive Inbound vs Outbound...

Angel Scale Biotech: Learn More   Brian Freeman, MD, co-founded Energesis to help overweight people lose weight by growing their energy-burning brown fat. Experiments in mice have shown this approach works with GLP-1 drugs such as Wegovy in accentuating weight loss. Great chat with a compelling repeat founder.   Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and Richardson.   Highlights: Sal Daher Introduces Brian Freeman Energesis: The...

Angel Scale Biotech: Learn More   My Walnut buddy Andy Bartlett, PhD brings great energy to the group and an expert’s perspective on computing. We talked about our favorite startups including Savran Technologies, evTS, and BioFeyn. He has interesting things to say about ChatGPT. We also had a great chat about his angel journey.   Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and Richardson.   Highlights: Sal Daher Introduces Andy Bartlett...

Angel Scale Biotech: Learn More   Kevin Majeres, MD, teaches cognitive behavioral therapy (CBT) at Harvard Medical School. CBT is the gold standard to treat mental health conditions without drugs. CBT can also help with workplace issues such as burnout or anxiety. Dr. Majeres (pronounced Majors) has built a digital platform, OptimalWork.com, to improve the quality of work life. I learned really useful things from this interview.   Sponsored by Purdue University entrepreneurship and Peter...

Jason Burke wants a better way for angels to invest in startups. He founded All Stage, the platform for angel investing that powers TBD Angels which he also co-founded.  In this illuminating interview Jason discusses how All Stage helps the angel ecosystem. We also chatted about Moolah Kicks, and Folia Health. Here's how All Stage's deal looks like in the All Stage platform: All Stage deal within the All Stage product Highlights:  ●      Sal Daher Introduces Jason Burke ●      All...

Angel Scale Biotech: Learn More   Brazilian startup MirScience Therapeutics is working on reversing muscle loss. I had an illuminating chat with co-founder Milena Peregrino, PhD about the technology and the company’s progress.    Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and Richardson.   Highlights: Sal Daher Introduces Milena Peregrino MicroRNAs and What They Do MirScience Therapeutics "... Keeping in mind that we're talking about...

Repeat founder Agustin Lopez Marquez, ex-nference, brings his AI savvy to food delivery with his new startup. Built on CloudKitchens’ infrastructure, Mowgli addresses pain points for diners, sous-chefs and drivers. Loved my chat with this brilliant and practical founder. Sample Mowgli’s homey meals from exotic places at https://khipi.com/. (delivers only to Boston & Cambridge for now)   Highlights:   ●      Sal Daher Introduces Agustin Lopez Marquez ●      "... my co-founder, who...

Angel Scale Biotech: Learn More   Repeat founder Todd Zion, PhD is back to update us on exciting developments at his second biotech startup, Akston Bio. We also geeked out a bit on how these magical proteins are concocted in the company’s bioreactors. Fun and instructive chat with a stellar founder.   Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and Richardson.   Highlights: Sal Daher Introduces Todd Zion Akston Bio's Founding Story "......

Angel Scale Biotech: Learn More   Rather than purloin my kids' Ritalin, I play EndeavorOTC daily to improve my attention and be sharper. Eddie Martucci, PhD is the founder of Akili that developed the app which is backed by real science. In fact, the kid's version is FDA-cleared to treat ADHD in 8-12 year olds. Don't miss this great chat.    Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and Richardson.   Highlights: Sal Daher Introduces...

Angel Scale Biotech: Learn More   The third time is the charm for Piction Health. Super founder Susan Conover is back to talk about the third iteration of their business model which is showing promise of scaling profitably. Her AI has ingested a million diagnosed images of hair and skin conditions and is now making dermatologists 15X more productive. See for yourself at PictionHealth.com.   Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and...

Angel Scale Biotech: Learn More   Rotator cuff tears are debilitating. What if you could take action to avoid them? Rabeeh Majidi, PhD founded OrthoKinetic Track to do just that through a wearable device and a predictive algorithm. Listen to our chat to learn more.    Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and Richardson.   Highlights: Sal Daher Introduces Rabeeh Majidi What OrthoKinetic Track is Solving "... What I would say is that...

Angel Scale Biotech: Learn More   Richard Vlasimsky is using AI to create a low-cost way of vastly expanding our ability to detect lung cancer early. His algorithm for detecting lung nodules in chest x-rays just got FDA clearance. Listen to this remarkable founder who’s done a lot with modest funding.   Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and Richardson.   Highlights: Sal Daher Introduces Richard Vlasimsky What IMIDEX is Solving...

Angel Scale Biotech: Learn More   Growing new cartilage in your knees is a dream about to become reality. Listen to Ben Holmes, PhD, co-founder of Nanochon, to learn about his promising technology. Shoutout to Richard Meiklejohn of M2D2 for the introduction.    Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and Richardson.   Highlights: Sal Daher Introduces Ben Holmes What Problem Nanochon is Solving "... That's really what we're looking to...

Angel Scale Biotech: Learn More   During COVID, Readlee, Drew Madson’s startup, offered teachers a highly effective way to measure and remedy reading deficits among online learners. This led to the company being acquired by Paper, the tutoring platform. An inspiring interview.   Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and Richardson.   Highlights: Sal Daher Introduces Drew Madson What Readlee is Solving Behind the Scenes of Readlee How...

Angel Scale Biotech: Learn More   Tech founder David Kessler discusses his journey as an angel investor in companies such as CleanFiber, Wasabi, and Hilltop Bio.   Sponsored by Purdue University enrepreneurship and Peter Fasse, patent attorney at Fish and Richardson.   Highlights: Sal Daher Introduces David Kessler "... This is like a very counterintuitive investment for angel investors, but it was angel-funded..." The Importance of Updates What Hilltop Bio Does "... This is why I...

Angel Scale Biotech: Learn More   Salvatore Viscomi, M.D. is CEO of Carna Health, a digital platform that is making it easier for patients with chronic conditions to do tests at home that would normally have to be done in the hospital.   Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and Richardson.   Highlights: Sal Daher Introduces Salvatore Viscomi What Carna Health is Solving "... We connect the device to our platform, we collect the...