Today's episode is going to feature one of the later monarchs from the Hellenistic era- Mithridates VI of Pontus. This is because his practice of trying to make himself immune to poison- called mithridatism- is biologically relevant and and continues to be influential until the 18th century. Sources for this episode: Jarcho, S. (1972), Medical Numismatic Notes, VII: Mithridates IV. Bulletin of the New York Academy of Medicine 48(8): 1059-1064. Kaberopoulos, D., Karamanou, M. and...

The Black Death in the 14th century is engrained in the popular consciousness. But how familiar is the first wave of the disease that happened in the 500s? In this episode, we explore what plague is, its evolution, strains and impact on the world of the 6th century according to Procopius. Sources for this episode: Achtman, M., Zurth, K., Morelli, G., Torrea, G., Guiyoule, A. and Carniel, E. (1999), Yersinia pestis, the cause of plague, is a recently emerged clone of Yersinia...

1-2% of the world's population have red hair. So, we're giving the phenomenon its own episode! Today, we discuss the gene/protein that causes red hair, as well as its psychological and possible medical effects... Sources for this episode: Bryant, NIH Research Matters (2021), Study finds link between red hair and pain threshold (online) (Accessed 12/01/2024). Gradwohl, S. C., Aranake, A., Abdallah, A. B., McNair, P., Lin, N., Fritz, B. A., Villafranca, A., Glick, D., Jacobsohn, E.,...

You asked, I delivered! In a sequel to our discussion in episode 58, we're going to shine a spotlight on two more thinkers during the Islamic Golden Age. Along the way we'll also see connections with later thinkers and a cameo from episode 69... Sources for this episode: Guerber, H. A. (1929), The Myths of Greece & Rome: Their Stories Signification and Origin. London: George G. Harrap & Company Ltd. Kaack, L. H. and Katul, G. G. (2013), Fifty years to prove Malthus right....

Darwin Day is upon us for the fourth time! To celebrate, let's follow Charles Darwin on the first part of his famous voyage between late 1831 and early 1832. We'll see him pour over cuttlefish, travel with veterans of the Napoleonic Wars and arrive in a young Brazilian Empire... Sources for this episode: Bannerman, W. M., Lobban, R. A. and Shaw, C. S., Encyclopedia Britannica (2023), History of Cabo Verde (online) (Accessed 08/02/2024). Bethell, L. (1968), The Independence of Brazil and...

A series of 5000 flowers pressed in the 16th century near Bologna have given scientists an opportunity to see human impacts and the rise of alien species. All while giving us an excuse to touch on what the Columbian exchange actually is... Sources for this episode: Anteric, I., Basic, Z., Vilovic, K., Kolic, K. and Andjelinovic, S. (2014), Which Theory for the Origin of Syphilis is True? Journal of Sexual Medicine 11: 3112-3118. Buldrini, F., Alessandrini, A., Mossetti, U., Muzzi, E.,...

It takes our sun 220 million years to orbit around the middle of our home galaxy. But that kind of timescale can be difficult to picture. So, using the International Stratigraphy Chart as a guidance for what different time periods mean in terms of millions of years, let's zoom out to the scale of a galactic year and see what happened in Earth's prehistory one cycle ago, two and so on. Sources for this episode: Bach, J. R. (2013), Paradigm paralysis in the management of neuromuscular...

Most people will have come across this term before, but what does it actually mean? Today, we'll be dissecting the terms microbiome and microbiota and looking at what can impact them. Sources for this episode: Amon, P. and Sanderson, I. (2017), What is the microbiome? Archives of Disease in Childhood- Education and Practice 102-258-261. Cremon, C., Barbaro, M. R., Ventura, M. and Barbara, G. (2018), Pre- and probiotic overview. Current Opinion in Pharmacology 43: 87-92. Kim, H.,...

Saint Helena is an island in the middle of the Atlantic Ocean, perhaps most famous as the final residence of Napoleon I, Emperor of the French from 1804 to 1814 and again briefly in 1815. However, there is also plenty of interesting ecology and anthropogenic impact to talk about. Join myself and my co-host on an old episode of Island Folk to find out more! The episode can be found at the following link: https://open.spotify.com/episode/1yP66nlH0ReAaZUWETXEHp?si=e894e255600c4bc0 Hope you...

This episode discusses what it says on the tin- two different models of the pace at which evolution happens. Punctuated equilibrium comes to us courtesy of Niles Eldredge and Steve Gould in the 1970s. We won't do a deep dive on which model is considered correct in this episode. However, punctuated equilibrium was appropriated by creationists in the 1980s as this issue became political- leading us to a convenient tangent on what exactly creationist philosophy is. Sources TBA.

Woolly mammoths are an iconic feature of the Ice Age in popular imagination. However, on today's episode, we will also see that they are the basis of a fun fact that may change your perception of the past... Sources for this episode: Ashman, D., Nature (2000), The sky was the limit for the Pyramid builders (online) [Accessed 10/10/2023]. Bartlett, C. (2014), The Design of the Great Pyramid of Khufu. Nexus Network Journal 16: 299-311. Clayton, P. A. and Price, M. J. (eds.) (2002), The...

A throwaway comment on Big Bang Theory got me thinking- could hybrid animals such as the griffin and the hippogriff be possible from a biological viewpoint? Using these two examples, we will explore the chromosome number of hybrid animals and see what it means for our mythical friends... Sources for this episode: Ewart, J. C. (1910), Are Mules Fertile? Nature 2143(85): 106. Geldenhuys, M. E. (1989), Die kariotipering van di lieu (Panthera leo). Journal of the South African Veterinary...

Introducing my newest venture- being one half of the Autocrat podcast! Autocrat is a podcast which aims to explore Roman civilisation from beginning to end. Beginning with the mythology and the stories of Aeneas and Romulus, the podcast will trace the journey through the Roman Kingdom, the Republic, the Empire and all the way to 1453 and beyond. Who knows if we'll make it that far, but we hope to have fun with it! The podcast can be found at...

It's episode 66, so I thought I'd cover a big event from 66 million years ago- the death of the dinosaurs! But it's not all doom and gloom- we will also take a look at how to prevent asteroid impacts in future. Sources for this episode: 1) Bottke, W. F., Vokrouhlický, D. and Nesvorný, D. (2007), An asteroid breakup 160 Mya as the probable sources of the K/T impactor. Nature 449: 48-53. 2) Brusatte, S. (2018), The Rise and Fall of the Dinosaurs: The Untold Story of a Lost World. London:...

Enrico Fermi is the man behind today’s episode, as we’re going to talk all about the Fermi paradox. In essence, why do we not see anyone else out there in the universe besides ourselves? Well, a number of solutions have been proposed- and they have to do with the second concept in today’s episode: the Great Filter. Sources for this episode: 1) Bailey, M. M. (2023), Could AI be the Great Filter? What Astrobiology can Teach the Intelligence Community about Anthropogenic Risks. arXiv preprint...

Hello everyone, just a quick note that the YouTube comments are active on all videos and in the community tab. Feel free to drop me a line there as an alternative to the show's email address and stay tuned for extra features such as polls in future!

In July 2023, the world experienced three consecutive days which were the hottest day on record. In fact, an interview with the Washington Post cited that it was the hottest day for 125,000 years. What does that mean? Well, today's episode will put that number into prehistorical and historical context, as well as compare our current global warming to an example of change from the Cretaceous. 1) Blum, M. G. B., and Jakobsson, M. (2010), Deep Divergence of Human Gene Trees and Models of Human...

On today's episode, we're going to range out into the cosmos for our inaugural episode in the world of astrobiology! We're going to ask the question: how many people could our galaxy support? Using some assumptions and approximations, we're going to see that the number dwarfs our current numbers here on Earth by quite some margin... 1) Asimov, I. (1952, 2016 edition), Foundation and Empire. London: HarperCollins Publishers Ltd. 2) Briggs, J. C. (2017), Emergence of a sixth mass extinction?...

Climate change is a big topic, and one we're not going to cover here. However, there are international efforts to try and do something about it. Today's topic is the United Nations Framework Convention on Climate Change (UNFCCC to its friends), which was first set up in the nineties. What exactly did it lead to? Well, that's what we're here for... Sources for this episode: 1) Bowman, W. D., Hacker, S. D. and Cain, M. L. (2017). Ecology (4th International Edition).Oxford: Oxford University...

Hello everyone, Vince here with a quick update on how the podcast schedule is probably going to work from now on. I'm likely as not going to try out a monthly schedule- meaning that a new After Alexander will show up on the first Saturday of every month and a Biopedia on the third Sunday- although that may vary depending if I have more or less time for it in a given month. Who knows, there may well be more than one episode a month if I'm lucky! There may also be some extra content in the...

It's that time of year again! This time round, I thought I'd put Charles Darwin's life into a little bit of historical context. This is because I imagine most people have a stereotypical image of him in their heads as a model Victorian gentleman. However, his life saw quite a few other historical events that wouldn't really spring to mind. For instance, would it have occurred to you that Darwin witnessed the closing years of the Napoleonic Wars? So, in honour of Darwin's birthday, let's...

This episode is going to be a return to genetics with an introduction to some phylogenetic terms. Groups can be monophyletic, paraphyletic or polyphyletic depending on who exactly is included. Confused? Well, that's what Biopedia is here to solve... Sources for this episode: 1) Campbell, N. A., Urry, L. A., Cain, M. L., Wasserman, S. A., Minorsky, P. V. and Reece, J. B. (2018), Biology: a global approach, 11th edition (Global Edition), Harlow, Pearson Education Limited. 2) Herron, J. C., and...

Another day, another episode of Island Folk! Sean Dettman and I discussed the concept of the island fortress as it was perceived in WW2 Britain. Basically, this is the idea that the inhabitants of the UK took comfort in the island nature of their country and the sea protecting them against hostile forces. Sean's upcoming publication on this subject was the focus of the episode's discussion. Along the way, we discuss connections to contemporary events, the paradigm of Britain's lack of...

In today's episode, we revisit an old blog post from all the way back in January 2021. George III of the United Kingdom is probably the person most famously associated with porphyria. However, what isn't as often discussed is what exactly it is. Moreover, as we will introduce in today's episode, it isn't just George Hanover who was affected with the condition; his wider family seems to have suffered from it too. We don't touch on this that much in the episode, but it in fact seems to stretch...