Autophagy
Listen now
Description
Dr Katja Simon tells us about her research on autophagy in red blood cells. Autophagy is the cellular process in which cells degrade their toxic waste and damaged organelles. In order to fit through small capillaries, red blood cells need to expel their nucleus and degrade their organelles. Dr Katja Simon's research focuses on how the lack of autophagy triggers DNA mutations leading to the possible development of leukemic cells. This might help us make better use of current therapies and develop new ones. Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK: England & Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/
More Episodes
Professor Skirmantas Kriaucionis aims to to elucidate the molecular function of DNA modifications in normal cells and cancer. Although all cells in our body have the same genome, they look different and perform different functions. Epigenetic modifications such as methylations ensure which sets...
Published 12/14/16
Published 12/14/16
Dr Ross Chapman studies the molecular events triggered by DNA damage detection, and why defects in these events lead to immune deficiency and cancer in humans. GENOME INTEGRITY Whilst controlled DNA breaks allow for our vast repertoire of antibodies, DNA damage happening out of context can lead...
Published 04/28/16