To commemorate the 60th anniversary of the publication of the structure of DNA, and the approaching centenary of the birth of Francis Crick, the Federation of European Biochemical Soceities (FEBS) and the Agouron Institute are sponsoring in conjunction with Gonville and Caius College a unique and historic meeting to be given by colleagues who were present at the time and by historians of science. This will be the last decennial meeting in which those colleagues are likely to be able to present lectures.