The Identification of Medicinal Products (IDMP) standards promise to harmonise how pharmaceutical products and substances are described around the world. But how will that benefit patients and who will make sure the standards are properly implemented? Uppsala Monitoring Centre’s Malin Fladvad and Olle Lagerlund discuss the advantages and challenges of this global standardisation effort. Tune in to find out: What the IDMP standards coverHow Uppsala Monitoring Centre will help create and...
Published 09/29/22
Published 09/29/22
Public trust in vaccines hinges on their safety – but to make sure vaccines are safe, we must have systems in place to detect and manage any side effects. Dr Madhava Ram Balakrishnan, medical officer for vaccine safety at the World Health Organization, discusses how to build an effective vaccine surveillance system and how to respond to safety crises when they occur. Tune in to find out: How safety surveillance differs between vaccines and drugsWhat the most common side effects of vaccines...
Published 08/24/22
Managing antimicrobial resistance (AMR) will require innovative solutions from many different disciplines. Could pharmacovigilance be one of them? Jean Marie Vianney Habarugira and Albert Figueras, who have been investigating how drug safety tools could help track AMR, think it’s time the two communities joined forces for good. Tune in to find out: How to code adverse drug reactions for optimal AMR surveillanceHow to use pharmacovigilance networks to track resistant pathogens and falsified...
Published 06/30/22
With the right care, people infected with HIV can lead long and healthy lives. But as with any life-long medical treatment, it is important to acknowledge and manage any side effects. Henry Zakumumpa from Makerere University School of Public Health tells us about the potential harms of new HIV therapies and the challenges faced by pharmacovigilance specialists in Uganda. Tune in to find out: How dolutegravir-based HIV therapies compare to earlier regimensHow pharmacovigilance data can help...
Published 04/29/22
Access to medical products has increased considerably in Africa in recent years, but safety monitoring systems haven’t exactly kept pace and many African countries still struggle to address safety issues. We sat down with Eleni Aklillu and Abbie Barry of the PROFORMA project to learn about their efforts to strengthen pharmacovigilance capacity in East Africa – especially within public health programmes. Tune in to find out: How comorbidities and genetic variation affect drug safety...
Published 03/24/22
People’s perception of risk can vary greatly from person to person, making it challenging for healthcare professionals to communicate benefits and harms of medicines in a balanced fashion. Alexandra Freeman from the Winton Centre for Risk and Evidence Communication discusses how to give patients the information they need to decide what's best for them. Tune in to find out: Why people perceive risks so differentlyWhy medical communicators should strive to inform rather than persuadeHow to...
Published 02/24/22
The loss of vital health records is a universal problem for refugees. When their medical information goes missing, patients are less likely to receive the care they need and more likely to be prescribed the wrong treatments. Thankfully, the International Society of Pharmacovigilance Egypt Chapter and the Palestine Red Crescent Society are taking on this problem, to reduce medication errors and improve reporting practices. This episode is part of the Uppsala Reports Long Reads series – the...
Published 01/27/22
Statistical tools can not only cut through the noise in large pharmacovigilance databases. They can also help identify more clinically meaningful patterns in the data. Uppsala Monitoring Centre’s Jim Barrett and Joe Mitchell explain how vigiGroup, a novel clustering algorithm, can bring value to signal detection. Tune in to find out: What the limits of traditional disproportionality analysis areHow clustering algorithms can improve current signal detection practicesHow vigiGroup has helped...
Published 12/16/21
With vaccine hesitancy on the rise and misinformation spreading like wildfire on social media, drug safety specialists may have a hard time knowing how to talk about side effects without affecting people’s trust in vaccinations. Anthony Cox from the University of Birmingham and Daniel Salmon from the Institute for Vaccine Safety share their best advice for balanced and responsible vaccine safety communication. Tune in to find out: Why we can’t allow bad actors to damage the drive for...
Published 11/03/21
It’s not always easy to choose the best medicine for a child. Some drugs are inappropriate for young patients, while others require special consideration or monitoring. For years, clinicians had only historical dogmas, word of mouth and their own experience to guide their choices. But a valuable new resource promises to change paediatric prescribing for the better. This episode is part of the Uppsala Reports Long Reads series – the most topical stories from UMC’s pharmacovigilance magazine,...
Published 10/05/21
Fuelled by disinformation and an array of other cultural and economic factors, vaccine hesitancy is one of the greatest global health communication challenges of our times. But to craft the empathetic and tailored communication strategies required to boost confidence in vaccines, we first need to understand the difference between anti-vaccination belief and vaccine hesitancy. This episode is part of the Uppsala Reports Long Reads series – the most topical stories from UMC’s pharmacovigilance...
Published 08/30/21
Genetic variation is one of the reasons people differ in their response to medicines. Understanding that variation can inform more refined choices of drugs and doses – ultimately preventing undesired side effects. Join us as we discuss past, present and future of pharmacogenomics with Uppsala Monitoring Centre’s Qun-Ying Yue. Tune in to find out: How genetic biomarkers can guide medicine use and dosing recommendationsWhat we need to effectively implement genetic-based prescribing in clinical...
Published 07/29/21
With COVID-19 vaccinations rolling at full speed in many countries, there’s a lot of talk about vaccine safety monitoring. But what exactly does that mean and how should we be interpreting data on side effects? Uppsala Monitoring Centre’s Helena Sköld and Annette Rudolph walk us through the basics of vaccine pharmacovigilance. Tune in to find out: how suspected side effects are reported and studied around the worldwhy a mere list of reported side effects says little about a vaccine’s safety...
Published 06/24/21
While COVID-19 vaccinations are picking up speed in many wealthy countries, citizens of lower-income countries still face a long wait ­– and where demand exceeds supply, black markets tend to form. So to curb the spread of substandard and falsified products, says drug regulatory specialist Danini Marin, we must ensure that COVID-19 vaccines are distributed equitably around the world. This episode is part of the Uppsala Reports Long Reads series – the most topical stories from UMC’s...
Published 05/27/21
Uppsala Health Summit participants Otto Cars, Eldar Shafir and Vanessa Carter provide their perspective on managing antimicrobial resistance through behaviour change.
Published 04/27/21
For pharmacovigilance manager Marco Tuccori, fighting the COVID-19 “infodemic” is a massive, but necessary, battle. Audio version of an Uppsala Reports article.
Published 03/26/21
Christina Ström Möller from Swedish biopharmaceutical company Sobi discusses the challenges of developing orphan drugs for rare diseases.
Published 02/26/21
Boosting pharmacogenomics research in Africa is set to improve treatment outcomes for African populations. Audio version of an Uppsala Reports article.
Published 02/03/21
Eugene van Puijenbroek from the Netherlands pharmacovigilance centre Lareb discusses the role of intuition and clinical reasoning in drug safety.
Published 12/17/20
Former UMC director Marie Lindquist looks back at her career in patient safety. Audio version of an Uppsala Reports article.
Published 11/26/20
The Institute for Safe Medication Practices offers advice to prevent medication errors with two-component vaccines. Audio version of an article from the Uppsala Reports magazine.
Published 10/23/20
Peter Doshi from the RIAT Support Center is fighting to improve the reporting of clinical trial data and enable better decision-making in medicine.
Published 09/30/20
Report from the Global Science Film Festival 2019, with tips for effective science communication and a focus on the storytelling power of film.
Published 08/27/20
New natural language processing method reveals related drug and reaction terms in pharmacovigilance case safety reports. Audio version of an article from the Uppsala Reports magazine.
Published 08/06/20