MET is the only known receptor for hepatocyte growth factor (HGF). Activation of the MET receptor by HGF binding triggers a large, multistep, tightly regulated and intricated signal transduction cascade. These signalling events also culminate in initiating almost all cellular processes defining the malignant phenotype. The goal of this V-learning module is to provide a scientific overview of the multidomain structure of MET and HGF, milestones in MET and HGF discoveries, to show signalling...