Alex is a leader in the field of meta-science, the science of science. He is doing important and interesting work on the science replication, author contributions and generally how to make science more open and transparent. In this episode we discuss: Meta-science, The Replication crisis, pre-registration, replication vs discovery science, agile science, funding, the file draw problem, publishing science, Elsevier, science communication, the role of tech and radical new models of science.