Show Notes for Episode 63 of GI Pearls * Artificial intelligence- aided colonoscopy does not increase adenoma detection rate in routine clinical practice – Am J Gastr * Estimated Burden of Screening for Barrett’s Esophagus in the United States – Gastro * Carvedilol Achieves Higher Hemodynamic Response and Lower Rebleeding Rates Than Propranolol in Secondary Prophylaxis – CGH * Screening for Colorectal Cancer – ACP Guidance Statement – Annals of IM * Cold...

Episode 62 Show Notes July 2023 * Comparison of endoscopic sleeve gastroplasty versus surgical sleeve gastrectomy: a database analysis. – GIE * Incidence and natural history of gastric high grade dysplasia in patients with FAP. – GIE * Association of Life Expectancy with surveillance colonoscopy findings and follow up recommendations in Older adults – Jama IM * Physician decision-making about surveillance in older adults with prior adenomas: results from a...

Episode 61 Show Notes June 2023 * Efficacy of a Second PPI Course After Steroid-induced remission in EOE refractory to initial PPI therapy. – ACG * AGA Clinical Practice Update on Management of Subepithelial Lesions encountered during routine Endoscopy: Expert Review – CGH * Prune juice Containing Sorbitol, Pectin and Polyphenol Ameliorates subjective complaints and Hard Feces while Normalizing Stool in Chronic constipation: A randomized placebo-controlleD Trial. – Am J...

Show Notes for GI Pearls Episode 60 * What is the Prevalence of Clinically Significant Endoscopic Findings in Subjects With Dyspepsia? Updated Systematic Review and Meta-analysis – CGH* Quality of upper GI endoscopy: a prospective cohort study on impact of endoscopist education – GIE* Association between endoscopist specialty and colonoscopy quality: a systematic Review and meta-analysis. – CGH* Net Remission Rates with Biologic Treatment in Crohn’s  Disease: A Reappraisal of the...

Show notes for Episode 59 GI Pearls Podcast * Cannabidiol for Functional Dyspepsia With Normal Gastric Emptying: a RCT. – Am J Gastro* Randomized Controlled Trial Investigating Cold Snare and Forceps Polypectomy among small POLYPs in Rates of Complete Resection: The TINYPOLYP Trial – Am J Gastro* Vonoprazan triple and dual therapy for Hpylori infection in the United States and Europe: RCT – Gastro* Aggressive or Moderate Fluid Resuscitation in Acute Pancreatitis – NEJM Tweet

Episode 58 Show notes * Cold versus hot snare resection with or without submucosal injection of 6-15mm colorectal polyps: RCT. – GIE* Prospective cohort study to investigate the safety of preoperative tumor necrosis factor inhibitor exposure in patients with inflammatory bowel disease undergoing intra-abdominal surgery.  – Gastroenterology* Clip Closure does not reduce risk of bleeding after resection of large serrated polyps: Results from a randomized trial. – CGH Tweet

Articles discussed * Clinically significant serrated polyp detection rates and risk for postcolonoscopy colorectal cancer: data from the New Hampshire Colonoscopy Registry – GIE* Polyps seen but not removed during index colonoscopy: an underestimated inefficiency in endoscopy practice. – GIE* Fecal Microbiota transplant is a good treatment for recurrent C.difficile and there were several randomized clinical trials showing it’s efficacy, mostly small, but with really good...

Episode 56 – New Short Format Articles discussed: * Once-only colonoscopy or two rounds of faecal immunochemical testing 2 years apart for colorectal cancer screening: preliminary report of a randomised controlled trial – Lancet Gastro Hep* Vedolizumab is associated with a lower risk of Serious Infectious than Anti-Tumor Factors Agents in Older Adults – CGH please feel free to add your comments on https://gipearls.com/category/podcast/ – just select the episode and leave...

Show notes for Episode 55 – June 2022 * Pooled Rates of Adenoma Detection by Colonoscopy in Asymptomatic Average Risk Individuals with Positive Fecal Immunochemical Test: A Systematic Review and Meta-Analysis – GIE* Long-Term Follow-up of the Italian Flexible Sigmoidoscopy Screening Trial – Annals of IM* Recurrence of Colorectal neoplastic polyps after incomplete resection  – annals of internal Medicine* A randomised controlled study shows supplementation of overweight and obese adults...

Show notes Episode 54 – May 2022 * A Randomized Controlled Trial of Cold Snare Polypectomy Technique: Technique Matters More Than Snare Wire Diameter – Am J Gastro* Outcomes for upper gastrointestinal bleeding during the first wave of the COVID-19 pandemic in the Toronto area – J Gastro and Hep * Endoscopic Surveillance of Barrett’s Esophagus – using old principles and new technology to improve Care. – Am J Gastro* Three signs of pneumoperitoneum on a Supine Radio-graph – CGH*...

Show Notes for Episode 53 * Lyophilised oral fecal microbiota transplantation for ulcerative colitis (LOTUS): a randomised, double-blind, placebo-controlled trial. – Lancet Gastro* Effect of prophylactic endoscopic clip placement on clinically significant post-endoscopic mucosal resection bleeding in the right colon: a single centre, randomized controlled trial – Lancet Gastro* Feasibility and diagnostic yield of small-bowel capsule endoscopy in patients with surgically altered gastric...

Episode 52 Show notes * Immediate versus Postponed Intervention for Infected Necrotizing Pancreatitis – NEJM* Benchmarking Adenoma Detection Rates for Colonoscopy: Results From a US-Based Registry – Am J Gastro* Colonoscopy-related Mortality in a Fecal-Immunochemical Test-based Colorectal Cancer Screening Program – CGH* AGA Clinical Practice Update on Endoscopic Surveillance and Management of Colorectal Dysplasia in IBD – expert review – Gastro* Should Treatment Indications for Chronic...

Show notes for Episode 51 * Role of routine second-look endoscopy in patients with acute peptic ulcer bleeding: meta-analysis of randomized controlled trials-  GIE* A Randomized Trial Comparing the Specific Carbohydrate Diet to a Mediterranean Diet in Adults with Crohn’s Disease – Gastroenterology* Comparative effectiveness and harms of antibiotics for outpatient diverticulitis. – Annals of IM* Colonoscopy Versus Fecal Immunochemical Test for Reducing Colorectal Cancer Risk: A...

* Histologic Changes caused by Injection of a novel submucosal lifting agent for endoscopic resection in GI lesions. – GIE* Prevalence of Barrett’s Esophagus and performance of societal screening guidelines in an unreferred Primary care Population of US veterans.  – GIE* The usefulness of olive oil enema in children with severe chronic constipation – J Ped Surg* Rates of Postoperative Recurrence of Crohn’s Disease and Effects of Immunosuppresive and Biologic Therapies – CGH* Histopathologic...

Show notes for Episode 49 for April 2021 * Effectiveness of Oral Vancomycin for Prevention of Healtchare Facility-onset C.diff infection in Targeted Patients during Systemic antibiotic Exposure – Clinical ID* The Detrimental Effects of oral Vancomycin – Letter to Editor – Clinical ID* Linked color imaging focused on Neoplasm detection in the Upper GI tract – randomised trial  – Annals of Internal Medicine* AGA clinical Practice Update on Medical Management of Colonic Diverticulitis:...

Show notes for Episode  48 March 2021 * Younger physicians and longer withdwaral times are associated with detection of advanced neoplasia in a large community practice. – CGH* It’s All The RAVE: Time to Give up on “Chronic Radiation Proctitis” Misnomer – Gastroenterology* Local immune response to food antigens drives meal-induced abdominal pain – Nature* Prevalence of  a First-Degree Relative with Colorectal Cancer and Uptake of screening among persons 40-54 years old. – CGH*...

Show notes for Episode  47, January 2021 * Endoscopic Recognition and management strategies for Malignant Colorectal Polyps: Recommendation of the US Multi-Society Task force on Colorectal Cancer – GIE* Polyp morphology: an interobserver evaluation for the Paris classification among international experts – AmJ Gastro* Outcomes in lower GI bleeding comparing weekend with weekday admission. – GIE* Efficacy and Safety of Ornithine Phenylacetate for Treating Overt Hepatic Encephalopathy in...

Show notes for Episode 46 for December 2020 * Sequential endoscopist-driven phone calls improve capture rate of adverse events after ERCP: a prospective study – GIE * Regular use of proton pump inhibitors and risk of type 2 diabetes: results from three prospective cohort studies – GUT * Long-Term Consequences of Undiagnosed Celiac seropositivity –  Am J Gastro* Hyperbaric oxygen therapy is effective in the treatment of inflammatory and fistulizing pouch complications. – CGH* Evaluating...

Show notes for Episode 45 for November 2020 *  Evaluation of Acute Mountain Sickness by Unsedated Transnasal Esophagogastroduodenoscopy at High Altitude – CGH* Early Colonoscopy Does Not Improve Outcomes of  Patients With Lower Gastrointestinal Bleeding: SRM – CGH * Adverse Events After Inpatient Colonoscopy in Octogenarians – J of Clinical Gastro* Comparative Efficacy of Drugs for the Treatment of Chronic Constipation – J of Clinical Gastro* Two vs one forward view examination of...

Show Notes for October 2020 – Episode 44 * A Quarter of Participants With Advanced Neoplasia  Have Discordant Results From 2-Sample Fecal  Immunochemical Tests for Colorectal Cancer Screening – CGH* Assessment of Clinical Conditions Associated with Splenic Infarction in Adult Patients – JAMA Internal Medicine* Unsedated colonoscopy – impact on quality indicators – Dig Dis Sci* The effect of green kiwifruit on gas transit and tolerance in healthy humans – Neurogastroenterology &...

Show notes for Episodes 43 – September 2020 * Levels of Vitamin D are low after Crohn’s disease is established but not before –  CGH* Rapid recurrence of EOE activity after successful treatment in the observational phase of a randomised trial. – CGH* Clinical outcomes of adults with eosinophilic esophagitis with severe stricture. – GIE* Quality of Colonoscopy: A Comparison  Between  Gastroenterologists and  Nongastroenterologists – Dis of colon & Rectum.* A Novel Score to Predict...

Show notes for Episodes 42 – July/August 2020 * Use of total underwater colonoscopy to navigate endoscopic challenges – CGH* Performance of radiographic imaging after incomplete colonoscopy for non-malignant causes in clinical practice. – GIE* Cognitive Deficit and white matter changes in persons with celiac disease: a population based study. -Gastroenterology* Endoscopic gastric body plication for the treatment of obesity – GIE* Cold snare piecemeal EMR of large sessile colnic polylps...

Show notes for Episodes 41 – June 2020 * Discrepancy between self-reported and actual colonoscopy polypectomy practices for the removal of small polyps – GIE* AGA Guidelines on the management of Moderate to Severe Ulcerative Colitis – Gastro * Resistance training increases muscle strength and muscle size in patients with liver cirrhosis. – CGH* Reduced incidence of Hepatic encephalopathy and higher odds of resolutions associated with eradication of HCV – CGH* Ammonia Levels do not...

Show notes for Episodes 40 – May 2020 * Choosing a prokinetic for your patient beyond metoclopramide – AmJ Gastro* Ultraprocessed Food Consumption and Risk of T2DM among participants of the NutriNet-Sante Prospective Cohort – JAMA Int Med* Diagnosis and Treatment of Clostridioides (Clostridium) difficile  Infection  in Adults in 2020 – JAMA* Clinical importance of cold polypectomy during the insertion phase in the left side of the colon and rectum: multicenter randomized controlled...