On Vaccination Against Smallpox is Edward Jenner's publication of his research into creating the smallpox vaccine. When in 1788 a smallpox outbreak hit Gloucestershire, Jenner noticed that people who worked with cattle and had caught the mild disease cowpox, which was not fatal, then never came...

Thomas Jefferson outlines the despot-like behavior of the King of Great Britain and declares that the United States of America will no longer recognize British rule. Part of FCIT's Historic American Documents Collection from Lit2Go.

The history of the United States can be traced through the significant documents that have guided and inspired generations of Americans. This document is the ten original amendments of the United States Constitution, authored by James Madison, passed by Congress on September 25, 1789 and ratified...