Dr Pavlos Msaouel: https://faculty.mdanderson.org/profiles/pavlos_msaouel.html 0:00 Pretext and context MD Anderson Cancer Center 1:42 The Early Experiences That Shaped Dr Msaouel 3:39 The System of Cancer Research In the United States 5:25 FDA Drug Approvals and Special Designations For Oncology 11:09 A trade-off in our current system 12:35 Whoops 😞 I misspoke 14:35 Randomized trials are not supposed to be representative of a population 18:10 Inference for the treatment of Katie Coleman...

Mug is here 😳 ► https://crowdmade.com/collections/chubbyemu  @chubbyemu  energy drink video ► https://youtu.be/tAtaIZD0Ebs A Student Ate Only Chips And Fries For 10 Years ► https://youtu.be/VINtwoyaF_8 A Mom Ate 5 Day Old Sushi 🍣 ► https://youtu.be/R0d6Dpx2li4 Vitamin B12 deficiency can cause neurologic problems. It's stored in the liver and isn't made in humans. It needs to be sourced via diet.

​ @chubbyemu  video: https://youtu.be/xtVvtsPgfew Heme Review Podcast: https://anchor.fm/chubbyemu Behind the scenes channel:  @BigEmus  Music by  @Lifeformed  ► https://lifeformed.bandcamp.com All Heme Review videos (playlist) ► https://www.youtube.com/playlist?list=PLAHeV2H_YiGUYhHOF4wRMCuqBIJvrnWqS Daddy Longlegs by Vengolis Loxosceles gaucho by Halies Some images by Getty Images References: CMS Malaque, RS Vetter, M Entres. Loxosceles spiders. Critical Care toxicology....

Caffeine Dry Scoop: https://youtu.be/sylqJ0NEVJw Happened while filming this video: https://youtu.be/LKNfFm0QDXQ Music by Lifeformed: https://lifeformed.bandcamp.com References: The Signaling Pathways Involved in the Anticonvulsive Effects of the Adenosine A1 Receptor. https://www.mdpi.com/1422-0067/22/1/320 Caffeine Withdrawal. https://www.ncbi.nlm.nih.gov/books/NBK430790/ A critical review of caffeine withdrawal: empirical validation of symptoms and signs, incidence, severity, and...

In 2015, a boy rubbed an entire tube of minty pain relief cream in-between his legs, and it caused his organs to shut down. Majority of modern men I believe are familiar with this action-- you may have accidentally applied it to the area yourself, or to the eyes, where it will hurt for a time that feels like an eternity. Chubbyemu video: https://youtu.be/Le-IKCLGT9A Boy Drinking his mom's essential oils: https://youtu.be/TZr0nt2hxbs References: Salicylate Toxicity from Exposure to a...

Fasting can be an effective tool for weight loss. However if used inappropriately, can result in some not good situations. The patient's situation in this case isn't quite like the intermittent fasting schedules that are popular today. Chubbyemu video: https://youtu.be/nQC_GDTNkQQ Heme Review commentary: https://youtu.be/tWlvWYGztYk Music by Lifeformed Tweet me: https://twitter.com/hemereview IG me: https://instagram.com/hemereview References: Mechanism of hypokalemia in magnesium...

Video version of this podcast: https://youtu.be/bq1kwlGhPyE Original Chubbyemu video: https://youtu.be/5ujTYLV2Qo4 Tweet me: https://twitter.com/hemereview IG me: https://instagram.com/hemereview Music by Lifeformed References: Fulminant Liver Failure in Association with the Emetic Toxin of Bacillus cereus. https://www.nejm.org/doi/full/10.1056/NEJM199704173361604 Sudden Death of a Young Adult Associated with Bacillus cereus Food Poisoning....

Chubbyemu video: https://youtu.be/3E75UvmY9GA Heme Review video on Renal Medullary Carcinoma: https://youtu.be/j7WGP6sJBLk Herman Connor Contact Cora Connor (Herman's sister): https://www.twitter.com/RMCAwareness Cora Facebook: https://www.facebook.com/RMCSupport IG me: https://www.instagram.com/hemereview Tweet me: https://www.twitter.com/hemereview

Video version of this podcast: https://youtu.be/j7WGP6sJBLk Chubbyemu video A Man Felt Pain In His Back. This Is What Happened To His Kidney. https://youtu.be/3E75UvmY9GA References: Renal medullary carcinoma. The seventh sickle cell nephropathy. Am J Surg Pathol. 1995 Jan;19(1):1-11. https://pubmed.ncbi.nlm.nih.gov/7528470/ A Model Linking Sickle Cell Hemoglobinopathies and SMARCB1 Loss in Renal Medullary Carcinoma. Clin Cancer Res. 2018 May 1;24(9):2044-2049....

Video version of this podcast: https://youtu.be/B8LLf7DkR5U Chubbyemu video of KT: https://youtu.be/LKNfFm0QDXQ Dr Bora Lim can be reached at https://www.twitter.com/naborala Burn pits are a waste management tool for armed forces overseas. However, the nature of waste today is different than half a century ago. The smoke, fumes, and particulate matter that have been observed emanating from these pits contain a heterogeneous variety of materials. Exact exposure levels are not known in...

Video version of this podcast: https://youtu.be/oP_mJmWrfTQ Chubbyemu video of this case: https://www.youtube.com/watch?v=WPxb2IG9MOk Featuring: Dr Sonal Jagasia, MD, MPH. Psychiatrist in private practice. Tweet me: https://www.twitter.com/hemereview IG me: https://www.instagram.com/hemereview FB me: https://www.facebook.com/hemereview Dextromethorphan is an over the counter cough medicine. It is for coughs. Misuse of it can cause life threatening side...

This episode is up to date as of 11 April 2021 Video version of this podcast: https://youtu.be/dsZzKzGdgTo Statement from water company CEO: https://www.youtube.com/watch?v=faCsru9Ctgk Inside Edition video about this case: https://www.youtube.com/watch?v=lmEpmyc7g9Y Local News talking about the water: https://www.youtube.com/watch?v=oGQJcnlk5ag On March 13, the FDA was alerted to five cases of acute non-viral hepatitis (resulting in acute liver failure) in infants and children that...

Chubbyemu video: https://www.youtube.com/watch?v=1MggKIfEld4 Heme Review video: https://www.youtube.com/watch?v=mPHXldh4_H4 Tweet me: https://www.twitter.com/hemereview IG me: https://www.instagram.com/hemereview  FB me: https://www.facebook.com/hemereview Chubbyemu YouTube channel: https://www.youtube.com/channel/UCKOvOaJv4GK-oDqx-sj7VVg Heme Review YouTube channel: https://www.youtube.com/channel/UCNSoNc9s67nfOGlCXSu5VsA References:  Potential Benefits of Dietary Fibre...

Video version of this interview: https://youtu.be/oLe9UdL-qIk Jill's Blog: https://throughthevalley.ca White Ribbon Project: https://twitter.com/TheWRP4LC LUNGevity Foundation: https://lungevity.org GO2 Foundation: https://go2foundation.org Lung Cancer Canada: https://www.lungcancercanada.ca Lung Foundation Australia: https://lungfoundation.com.au Lung Cancer Europe (LUCe): https://www.lungcancereurope.eu Tweet me: https://www.twitter.com/hemereview IG me:...

Please note the CONTENT WARNING at the beginning-- there's a reason I can't make the videos as described in this episode. They may surface in a different form at some time in the future. Heme Review YouTube: https://www.youtube.com/channel/UCNSoNc9s67nfOGlCXSu5VsA Tweet me: https://www.twitter.com/hemereview IG me: https://www.instagram.com/hemereview FB me: https://www.facebook.com/hemereview --- Support this podcast: https://anchor.fm/chubbyemu/support

Video of this interview: https://youtu.be/o15HCjtSkug Chubbyemu video https://youtu.be/ChPeG19qKUo Christopher's recount of his case: https://youtu.be/7BpymtR2vpA Tweet me: https://www.twitter.com/hemereview IG me: https://www.instagram.com/hemereview FB me: https://www.facebook.com/hemereview 2,4-Dinitrophenol (DNP) is a chemical that is not approved for weight loss. It is a classic case of efficacy, but without safety in the setting of weight loss. This setting of weight loss can be...

Patient CE's personal recount of case: https://youtu.be/7BpymtR2vpA Patient CE's  Interview: https://youtu.be/o15HCjtSkug Chubbyemu video on this case: https://youtu.be/ChPeG19qKUo Heme Review video version: https://youtu.be/jgDUMNaVqHg 2,4-Dinitrophenol (DNP) is a chemical that is not approved for weight loss in the United States. It is a classic case of efficacy, but without safety in the setting of weight loss. This setting of weight loss can be prone to chemical misuse, further...

Based on N Engl J Med 2020; 383:1263-1275. https://www.nejm.org/doi/full/10.1056/NEJMcpc2002420 Video version of this podcast: https://youtu.be/8lGmvFkAMOU Chubbyemu video of this case: https://youtu.be/qg76qIZ4BQ8 Laxative Brownie video from 2017: https://youtu.be/TMy0vJfKvzI Tweet me: https://twitter.com/hemereview  IG me: https://instagram.com/hemereview  FB me: https://facebook.com/hemereview Licorice candy has glycyrrhizin which increases cortisol (stress hormone) levels in the...

YouTube Video Version: https://youtu.be/ZNA_NtcutYY Chubbyemu Video: https://youtu.be/NaAFOrudj0g References: The Pharmacology and Use of H1-Receptor-Antagonist. N Engl J Med 1994; 330:1663-1670 Advances in H1-Antihistamines. N Engl J Med 2004; 351:2203-2217 Cardiac arrest caused by diphenhydramine overdose. Acute Med Surg. 2018 Oct; 5(4): 380–383. IV Lipid Emulsion Infusion in the Treatment of Severe Diphenhydramine. Am J Case Rep. 2019 May 29;20:758-763. Diphenhydramine with...

YouTube Video Version: https://youtu.be/QSXzRWiuvxE  Chubbyemu video of this case ▶️ https://youtu.be/fr8bp8a2QS4 The Body After Drinking A Snowglobe ▶️ https://youtu.be/elzijduKNS8 The Body After 2 Gallons Coffee In 3 Hours ▶️ https://youtu.be/rn-WLpa_nyQ Tweet me: https://www.twitter.com/hemereview FB me: https://www.facebook.com/hemereview IG me: https://www.instagram.com/hemereview Music by  @Lifeformed  Heatstroke is a serious problem and the heatwaves that cause it, claim more...

Methanol-contaminated hand sanitizer has been on sale in the USA during COVID-19 pandemic. The FDA has issued a warning against this, and have listed the brands. Most stores that are selling these brands have pulled them from shelves. Methanol is a toxic alcohol that can cause blindness. Its antidote is ethanol, which is the alcohol that people drink casually, however management needs to be done by a healthcare professional, as methanol hangs around in the body for several days. The case...

This episode is about the pathophysiology on crystallopathies. The cellular pathways involved unify multiple concepts and multiple branches of medicine, from toxicology to cardiology to rheumatology and oncology. Heme Review YouTube Channel: https://www.youtube.com/channel/UCNSoNc9s67nfOGlCXSu5VsA References: [0] Crystallopathies. N Engl J Med 2016; 374:2465-2476. https://www.nejm.org/doi/full/10.1056/NEJMra1601611 [1] Recent advances in the mechanisms of NLRP3 inflammasome activation and...

Video version of episode: https://www.youtube.com/watch?v=elzijduKNS8 Chubbyemu case: https://youtu.be/UrbylXMU8Mw  Most snowglobes are just made of water, but some can contain ethylene glycol. Most of those usually don't contain enough ethylene glycol to cause damage, but keep the word "usually" in mind. A homemade snowglobe can contain concentrations of anything, which is what happened in this case. Ethylene glycol can cause a profound high anion gap metabolic acidosis, and we'll explain...

Max recommended amount of caffeine per day is 400mg. @Chubbyemu case report video ► https://youtu.be/wj_AOzSSDMM  Video version of this episode ► https://youtu.be/rn-WLpa_nyQ Instagram me: https://www.instagram.com/hemereview  Facebook me: https://www.facebook.com/hemereview  Tweet me: https://www.twitter.com/hemereview     Music by  @Lifeformed  Some caffeine is OK. 1-2 cups of coffee can generally be ok.  Unreasonably large amounts of caffeine NOT OK.   References:  [0] Hensher...