The contribution of adverse events to the deaths of patients in the pediatric ICU (PICU) who die despite a low predicted mortality risk is unknown. Elizabeth H. Mack, MD, MS, FCCM, is joined by Carin W. Verlaat, MD, to discuss adverse events in low-risk nonsurvivors compared with low-risk survivors and high-risk PICU survivors and nonsurvivors and the contribution of adverse events to mortality. The podcast centers around the article, Adverse Events in Pediatric Critical Care Nonsurvivors With a Low Predicted Mortality Risk: A Multicenter Case Control Study (Verlaat C, et al. Pediatr Crit Care Med. 2023;24:4-16). Dr. Verlaat is a pediatric intensivist at Radboud University Medical Center in Nijmegen, Netherlands.