Who Should Get the New Alzheimer Disease Drug? Could Universal Donor Blood Be Made in the Lab? More Than 1 in 4 Nurses Say They Plan to Leave Health Care Related Content: Who Should—and Can—Get Lecanemab, the New Alzheimer Disease Drug? Could Universal Donor Blood Be Made in the Laboratory? Overworked and Understaffed, More Than 1 in 4 US Nurses Say They Plan to Leave the Profession

In this Q&A, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, and Bernard S. Chang, MD, MMSc, a neurologist and dean for medical education at Harvard Medical School, discuss how AI will change medical education, admissions, and teaching the future generation of physicians and clinicians. Related Content: AI Will—and Should—Change Medical School, Says Harvard’s Dean for Medical Education Transformation of Undergraduate Medical Education in 2023

In this Q&A, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, talks with Andrew Bindman, MD, an internist and the executive vice president and chief medical officer for Kaiser Permanente, about AI implementation and the importance of building trust in a health care system. Related Content: Kaiser Permanente’s CMO: How AI Might Help Clinicians Address Patients’ Social Risk Factors

In this Q&A, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, interviews Kedar S. Mate, MD, an internal medicine physician, President and Chief Executive Officer at the Institute for Healthcare Improvement, and faculty at Weill Cornell Medical College, to discuss AI’s role in health care quality and approaches to improving health equity. Related Content: New AI Tools Must Have Health Equity in Their DNA

In this Q&A, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, and Kevin B. Johnson, MD, MS, the David L. Cohen and Penn Integrates Knowledge University Professor of Pediatrics, Informatics, Engineering, and Communication at the University of Pennsylvania, discuss how AI can reduce clinician burden and streamline health system functions. Related Content: Electronic Health Records Failed to Make Clinicians’ Lives Easier—Will AI Technology Succeed?

Should Consumers Buy a Blood Test to Evaluate Their Alzheimer Disease Risk; How Wildfire Smoke Harms Health Related Content: Consumers Can Now Buy a Blood Test to Evaluate Their Alzheimer Disease Risk, but Should They? Raging Wildfires Are Exposing More People to Smoky Air—Here’s What That Means for Health

In this Q&A, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, and Ida Sim, MD, PhD, a primary care physician and UCSF’s Chief Research Informatics Officer, discuss generative AI, large language models, and the ways in which AI could affect humanity in medicine. Related Content: The Promise and Pitfalls of AI in the Complex World of Diagnosis, Treatment, and Disease Management

In this Q&A, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, interviews Michael Howell, MD, MPH, a pulmonologist and chief clinical officer at Google, to discuss the evolution of AI and what we should expect next for AI and health care. Related Content: Google Health’s Chief Clinical Officer Talks About Incorporating AI in Health Care

Many health care professionals are already dealing with the effects of climate change. In this Q&A, the World Health Organization’s first-ever Special Envoy for Climate Change and Health, Vanessa Kerry, MD, MSc, joins JAMA Medical News Director Jennifer Abbasi to discuss how a changing climate and extreme weather events are impacting human health, what clinicians should expect in the years ahead, and how they can help protect patients—and the planet. Related Content: Critical Care...

What to Know About the First Pill Approved for Postpartum Depression; Will the Updated COVID Vaccines Protect Against the New Variant? CDC Assesses Risk From BA.2.86, Highly Mutated COVID-19 Variant Related Content: A Fast-Acting Pill Received Approval for Postpartum Depression—Is It a Game Changer? What to Know About EG.5, the Latest SARS-CoV-2 “Variant of Interest” CDC Assesses Risk From BA.2.86, Highly Mutated COVID-19 Variant

Treating Long COVID’s Mental Health Symptoms in Primary Care; This Fall’s COVID-19 Vaccine Will Target Omicron XBB Subvariants—Who Needs to Get It; Avian Influenza Update Related Content: HHS Urges Primary Care Clinicians to Help Patients Manage Long COVID’s Mental Health Symptoms Vigilance Urged Against Bird Flu Amid Ongoing Outbreaks in Mammals This Fall’s COVID-19 Vaccines Will Target Omicron XBB Subvariants, but Who Needs Them Remains to Be Seen

Data on a new crop of hormone analogues for weight loss—including an oral version of semaglutide and the triple agent retatrutide—were recently presented at the American Diabetes Association’s annual Scientific Sessions. Robert Gabbay, MD, PhD, the ADA’s chief scientific and medical officer, speaks with JAMA’s Jennifer Abbasi about this and other clinical data presented at the meeting. Related Content: New Weight Loss Drugs Make Headlines at Diabetes Meeting

The 2021 US maternal mortality rate is more than 10 times the rate of other high-income countries, according to a March 2023 CDC report. In this Q&A, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, is joined by Monica McLemore, PhD, MPH, RN, University of Washington, Audra Meadows, MD, MPH, UC San Diego, and Joia Crear-Perry, MD, founder and president of the National Birth Equity Collaborative, to discuss these concerning numbers and why preventable death rates are worsening...

Sugar Substitutes Don’t Help Weight Control and May Increase Risk of Heart Disease and Diabetes, WHO Warns; Social Media and the Youth Mental Health Crisis Related Content: Sugar Substitutes Don’t Help Weight Control and May Increase Risk of Heart Disease and Diabetes, WHO Warns Surgeon General Sounds the Alarm on Social Media Use and Youth Mental Health Crisis

JAMA Deputy Editor and JAMA Oncology Editor Mary (Nora) L. Disis, MD, speaks with Kimmie Ng, MD, MPH, chair of the meeting’s Scientific Program Committee and associate chief of the Division of Gastrointestinal Oncology at Dana-Farber Cancer Institute. Related Content: Highlights From the ASCO Annual Meeting—New Approaches to Cancers of the Blood, Brain, Lung, and More

JAMA Senior Editor Kristin L. Walter, MD, MS, speaks with Debra Boyer, MD, MHPE, about important research studies and keynote addresses presented at the American Thoracic Society International Conference in May 2023. Dr Boyer is a pediatric pulmonologist and chief medical education officer at Nationwide Children’s Hospital in Columbus, Ohio, and was cochair of this year’s conference. Related Content: COPD Mortality, Goals-of-Care Conversations in Serious Illness, and Advocating for...

What Clinicians Need to Know About “Tranq”; As Laws Restricting Health Care Surge, Some US Physicians Choose Between Fight or Flight Related Content: As Laws Restricting Health Care Surge, Some US Physicians Choose Between Fight or Flight Here’s What to Know About Xylazine, aka Tranq, the Animal Tranquilizer Increasingly Found in Illicit Fentanyl Samples Risk of Parkinson Disease Among Camp Lejeune Veterans

JAMA Fishbein Fellow Revital Marcus, MD, talks with American Academy of Neurology president-elect and meeting science committee chair Natalia Rost, MD, about hot topics at this year’s conference in Boston, including new Alzheimer disease drugs, long COVID and the central nervous system, and a nasal spray for migraines. Related Content: New Alzheimer Disease Drugs, Long COVID and the Central Nervous System, and a Nasal Spray for Migraines—Highlights From the 2023 American Academy of...

More than 14 000 infectious diseases physicians, clinical microbiologists, and public health professionals gathered in Copenhagen, Denmark, in April for the European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), Europe’s largest infectious diseases conference. In this Medical News Q&A, JAMA Deputy Editor Preeti N. Malani, MD, MSJ, discusses highlights from the congress with Jacob Moran-Gilad, MD, MPH, ECCMID program director. Related Content: Artificial...

As Ozempic’s Popularity Soars, Here’s What to Know About Semaglutide and Weight Loss; Implementation Science Seeks to Translate Research Into Practice; What a Study of Hibernating Bears Tells Us About Deep Vein Thrombosis Related Content: As Ozempic’s Popularity Soars, Here’s What to Know About Semaglutide and Weight Loss It Takes an Average of 17 Years for Evidence to Change Practice—the Burgeoning Field of Implementation Science Seeks to Speed Things Up What a Study of Hibernating...

Physicians Say an Idaho House Bill That Would Criminalize Administering mRNA Vaccines Is an Attack on the Medical Profession—Even If It Doesn’t Become Law; The Debate Over Whether to Make Daylight Saving or Standard Time Permanent; Expanded Family Leave Policies May Ease Burden for Residents Related Content: Physicians Say an Idaho House Bill That Would Criminalize Administering mRNA Vaccines Is an Attack on the Medical Profession—Even If It Doesn’t Become Law Groundswell Grows for...

JAMA Medical News Senior Staff Writer Melissa Suran, PhD, MSJ, speaks with Douglas Drachman, MD, about late-breaking research discussed at the annual conference of the American College of Cardiology and World Congress of Cardiology. Dr Drachman—who chaired this year’s conference—is an interventional cardiologist at Massachusetts General Hospital, where he is also director of education in the cardiology division. Related Content: Highlights From the American College of Cardiology’s 2023...

More than 2 million individuals in the US are chronically infected with hepatitis C, and nearly 15 000 die every year. Antivirals are available but are not reaching the majority of infected individuals. In this Q&A, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, and Francis S. Collins, MD, PhD, discuss a plan to eliminate hepatitis C included in the Biden-Harris 2024 budget proposal. Related Content: A National Hepatitis C Elimination Program in the United States...

Conference clinical cochair Diane Havlir, MD, a professor of medicine at the University of California, San Francisco, sits down with JAMA Deputy Editor Preeti Malani, MD, MSJ, about research highlights presented at the 30th annual CROI, held in Seattle. The infectious disease experts discuss postexposure prophylaxis for sexually transmitted infections, a new protease inhibitor for COVID-19, goals for preventing HIV transmission, and more. Related Content: Highlights From CROI, the...

Bird Flu Has Begun to Spread in Mammals—Here’s What’s Important to Know; Questions Remain About What Should Go Into Annual COVID-19 Vaccines; Long COVID Linked With Unemployment in New Analysis; As Superbugs Flourish, Bacteriophage Therapy Recaptures Researchers’ Interest. Related Content: Bird Flu Has Begun to Spread in Mammals—Here’s What’s Important to Know Questions Remain About What SARS-CoV-2 Variants Should Go Into the Annual COVID-19 Vaccines Proposed by the FDA Long COVID Linked...