In this episode of "Office Hours Live," Dr. Eric Trexler and Dr. Eric Helms delve into various aspects of muscle building and training strategies. They challenge common misconceptions about body fat levels and muscle gain, discussing how being extremely lean isn't necessary for effective bulking and may even hinder muscle growth. The conversation covers troubleshooting unsuccessful bulks, exploring factors like diet, training frequency, and exercise selection. They emphasize the importance of exercise variety and rep range variation in hypertrophy programs, particularly for high-frequency training. The hosts address numerous questions on specific exercises and muscle groups, including abdominal training, hamstring development, and anterior deltoid work. They also discuss the role of lactate in exercise and clear up misconceptions about its use as a fuel source. The episode concludes with a conversation about GLP-1 agonists in natural bodybuilding. The MASS crew goes live for Office Hours every Wednesday night at 7pm eastern time. Be sure to join us for a future episode! If you'd like to submit a question ahead of time, please use this link: https://massresearchreview.com/office-hours/ Time stamps: 0:00 - Introduction and opening remarks. 1:37 - Discussion about P-ratios, body fat levels, and muscle building. Being lean isn't necessary for effective bulking. Higher body fat individuals can gain muscle without a large surplus. 7:37 - Conversation about being "too lean" to build muscle efficiently. Evidence suggests very lean individuals (below 8% body fat for males) struggle to gain muscle without fat gain. Initial weight regain after competition is often predominantly fat. 24:18 - Addressing questions about troubleshooting unsuccessful bulks. Factors to consider include diet, timeline, protein intake, and training program. The importance of exercise variety and rep ranges is discussed. 33:23 - Exploration of high-frequency training and exercise selection. Recommendations are given for training muscle groups 5+ times per week. The importance of exercise variety and rep range variation is emphasized. 44:25 - Rapid-fire questions about exercise selection and programming. Topics include flies vs. presses, hamstring exercises, face pulls, and anterior deltoid training. Recommendations are provided for exercises to include in most hypertrophy programs. 1:01:20 - Questions about abdominal training, lactate supplementation, and hamstring development. The importance of direct ab work for hypertrophy is discussed. Misconceptions about lactate as a fuel source are addressed. Recommendations for complete hamstring development are provided. 1:13:28 - Final questions, closing remarks, and upcoming events. Discussion on GLP-1 agonists and natural bodybuilding.