From the #mediaX2015 Conference “Writing the Code for Personal Relevance”; Allan Reiss, Howard C. Robbins Professor of Psychiatry and Behavioral Sciences and Professor of Radiology, Director, Center for Interdisciplinary Brain Sciences (CIBSR) at Stanford University, discusses being at a fascinating inflection point in our understanding of human brain function and dysfunction. In the first part of this talk, Allan describes his research designed to improve understanding of communicative and social complexities in human social interaction with the goal of providing a more complete and nuanced background for understanding human-human interaction. In the second part of the talk he briefly describes technology-enhanced advances in personalized brain medicine that hold promise for revolutionizing the approach to common (and often devastating) brain disorders such as autism, learning disabilities and dementia.