In this episode of OnAir, sleep clinician Prof. Dr Manuel Sánchez-de-la-Torre and host Daniela Ehrsam-Tosi discuss the potential benefits of patient phenotyping for obstructive sleep apnoea. Prof. Dr Sánchez-de-la-Torre explores why patient phenotyping can be relevant during diagnosis, for making effective treatment decisions, and during the follow-up stage. He highlights the role of patient phenotype in predicting responses and understanding neutral effects, with a particular focus on blood...

In this episode of OnAir, clinical expert Professor Christoph Schöbel and host Daniela Ehrsam-Tosi discuss sleep quality and sleep disorders. There’s a growing awareness of the importance of sleep for our cardiovascular system and our general health and wellbeing. At the same time, our ability to get good sleep is increasingly challenged by everything from late-night scrolling to irregular work schedules, stress and anxiety. It’s thought that 10-30% of people worldwide suffer from insomnia1,...

In this episode of OnAir, we ask whether treatment-adherent OSA patients could be lowering their cardiovascular risk while they sleep. Professor Frédéric Gagnadoux and host Nina Wiklund explore the design, results and implications of his recent 5,000-patient cohort study, which indicates that CPAP can deliver a significant reduction in major adverse cardiovascular events. They ask which patients are likely to benefit, discuss the importance of hours of usage, and consider the tools that...

The world has changed profoundly in the 25 years since the internet became mainstream. Is it finally healthcare’s turn to experience a dramatic data-driven transformation? Daniela Ehrsam-Tosi and ResMed’s Chief Medical Officer Carlos Nunez explore the risks, realities and research potential of real-world data and deep machine learning. Their discussion starts with the perennial challenges of rising healthcare costs and ageing populations and invites us to look to a future where our data isn’t...

Which factors make a real difference when it comes to keeping NIV patients comfortable, motivated and well cared for at home? In this episode of the OnAir podcast, respiratory expert Dr Jean-Michel Arnal and host Nina Wiklund discuss key issues in the delivery of home NIV, with a particular focus on troubleshooting, telemonitoring and patient engagement. As an ICU physician and the author of both a popular book1 and a recent article on home ventilation monitoring2, Dr Arnal has a deep...

Whether you attended ERS 2023 in person or are planning to catch up with the presentations and posters online, you won’t want to miss this episode of the OnAir podcast. As well as giving a flavour of the wide variety of topics covered, guests Adam Benjafield and Leanne Kaye share their conference highlights and key takeaways. The discussion ranges from the potential of behavioural science to drive PAP therapy adherence to the importance of personalised therapy, digital health and...

In this episode of OnAir, we explore how Sweden is shaking up its approach to the diagnosis and treatment of obstructive sleep apnoea. Professor Ludger Grote explains the background and benefits of the Swedish National Sleep Guidelines, which are part of a concerted effort to improve diagnosis, waiting times, treatment and outcomes for patients across the country. The new, comprehensive approach is based on a diagnostic framework and treatment matrix that has been developed using registry...

Following our previous podcast, which delved into the evolution of home high-flow therapy (HFT) and its implications for patient care, Dr Maxime Patout returns to offer more insights into the topic. This time round he describes the objectives of the large HiFAE trial he’s leading to assess the benefit of HFT when initiated after a severe exacerbation of COPD. Focused on French patients with severe forms of the condition, the study – which saw its first patient enrolled in late 2022 – aims to...

In this episode we’re joined by Dr Maxime Patout, who’s at the forefront of new research into home high-flow therapy (HFT). Listen now to find out why he thinks the evolving role of home HFT – especially in out-of-hospital care – means we’re on the verge of important change in respiratory medicine, with benefits for patients, healthcare professionals and healthcare systems. If you’d like to hear more from Dr Patout on this topic, tune in next time, when he’ll be offering insights into the...

In this episode, the focus is on the relationship between clinical outcomes, financial costs and societal impact. Dr Patrick Murphy explains the importance of collecting robust health economic data, using the example of the HOT-HMV trial that explored home NIV for COPD. If you’re interested in health economics, value-based healthcare, clinical commissioning or simply appreciate clear and informed discussion of a critical aspect of modern clinical research, you’ll want to tune in. Listen to...