The presentation covers the history of the discovery and development of rational antimicrobial chemotherapy before describing the terms used in discussing antibiotics and antibiotic resistance. The tests used to determine susceptibility to antibiotics in the laboratory are described as are the possible interactions, both negative and positive, that may occur when more than one antibiotic is used. The concept of “selective toxicity” is introduced before the presentation moves on to consider...

The presentation covers the history of the discovery and development of rational antimicrobial chemotherapy before describing the terms used in discussing antibiotics and antibiotic resistance. The tests used to determine susceptibility to antibiotics in the laboratory are described as are the possible interactions, both negative and positive, that may occur when more than one antibiotic is used. The concept of “selective toxicity” is introduced before the presentation moves on to consider...