Welcome to The Brain Podcast - the official podcast for the journal Brain and sister journal Brain Communications. In this episode we chat with Dr Georgia Melli, senior author of the article entitled: Tau protein quantification in skin biopsies differentiates tauopathies from alpha-synucleinopathies She discusses the use of skin biopsy to quantify pathological tau protein as an accessible and useful clinical tool in the diagnosis of neurodegenerative diseases.   Check out the full article on the Brain website: https://doi.org/10.1093/brain/awac161 This episode was hosted, edited and produced by Xin You Tai; co-hosted by Sarosh Irani; co-produced by Joanne Bell; original music by Ammar Al-Chalabi.