Dr. Andy Spry, Consultant to the Planetary Protection Officer, NASA April 21, 2023 In this episode, we discuss NASA's Office of Planetary Protection, which focuses on mitigating contamination risk for space missions. Their efforts cover both forward contamination—ie, contaminating extraterrestrial bodies with organisms from Earth—and backward contamination—ie, contaminating Earth with extraterrestrial life. Planetary protection functions much like laboratory biosafety, but on a much larger scale! The Planetary Protection office is responsible for developing and implementing the processes and standards necessary to ensure cleanliness and containment, and these considerations are part of the long-term planning that goes into all of NASA's space missions, including historical, current, and future efforts to return sample materials collected from the Moon, asteroids, and Mars.