Description
In this episode I have tried to simplify some stuff about diabetic ketoacidosis for the residents and the first time consultants. Its a huge topic and just one episode does not do justice to it. But you do not have to follow what I say. Please do your own research too. You can go through the following the references -
1. Canadian Diabetes Association Clinical Practice Guidelines Expert Committee; Goguen J, Gilbert J. Hyperglycemic emergencies in adults. Can J Diabetes. 2013 Apr;37 Suppl 1:S72-6. doi: 10.1016/j.jcjd.2013.01.023. Epub 2013 Mar 26. PMID: 24070967.
2. Self WH, Evans CS, Jenkins CA, et al. Pragmatic Critical Care Research Group. Clinical Effects of Balanced Crystalloids vs Saline in Adults
With Diabetic Ketoacidosis: A Subgroup Analysis of Cluster Randomized Clinical Trials. JAMA Netw Open. 2020 Nov 2;3(11):e2024596. doi:
10.1001/jamanetworkopen.2020.24596. PMID: 33196806; PMCID: PMC7670314.
3. https://emcrit.org/ibcc/hypokalemia/#top
4. https://emcrit.org/ibcc/dka/#definition_&_severity_of_DKA
5. Tran TTT, Pease A, Wood AJ, et al. Review of evidence for adult diabetic ketoacidosis management protocols. Front Endocrinol (Lausanne). 2017;8:106. doi:10.3389/fendo.2017.00106
6. Fort P, Waters SM, Lifshitz F. Low-dose insulin infusion in the treatment of diabetic ketoacidosis: bolus versus no bolus. J Pediatr 1980;96:36e40.
7. Butkiewicz EK, Leibson CL, O’Brien PC, et al. Insulin therapy for diabetic ketoacidosis. Bolus insulin injection versus continuous insulin infusion. Diabetes Care 1995;18:1187e90.