Ketamine has found wide uses since the 1960s: As a painkiller, an anesthetic, a street drug consumed at raves, and -- now -- considered by many to be an exciting new treatment for depression. We explore how ketamine was developed here in Detroit, at the Parke-Davis pharmaceutical company, with help from a Wayne State University chemistry professor, and later tested at the now-closed Lafayette Clinic facility in Detroit. Credit to: The BBC and The Tim Ferriss Show.

Broadcaster Fran Harris's life was a lifetime of firsts. She was the first woman newscaster in Detroit radio during World War II, persuading her bosses at WWJ to abandon its "guys only" tradition. And when television came along in Detroit on Channel 4 in 1946, she was on the air for that, too. When she retired from the station in 1974, some 200 women showed up at her goodbye party, grateful to Harris for the barriers she broke. We have a tape of a 1989 Harris interview, and talk with Michigan...

A longstanding community called Mexicantown on Detroit's southwest side has persevered for around a century. The area of restaurants, shops, and bakeries anchors a key ethnic community in Detroit. For many, the journey here was prompted by a search for jobs. We explore the rise of the community, and the decline when Depression-era policies due to racism sent many Mexican-Americans packing for Mexico. We talk with Maria Elena Rodriguez and Elena Herrada and explore how this neighborhood came...

Thousands of phonograph records were destroyed, as were thousands of needles used on the old-style record players. Teenage sleuths were conducting their own investigations in the great conspiracy theory of the fall of 1969: Beatle Paul McCartney had died, but that his death was covered up. However, as the theory went, clues could be found in the obscure nooks and crannies of Beatle records.  Weird? The rumor took root at WKNR-FM in Dearborn, and The Michigan Daily, the University of...

Sometime in the mid-1940s, an Italian immigrant bar owner by the name of Gus Guerra started making pizzas in his joint to bring in a few extra dollars. Decades later, Gus’s creation is big business, and world-renowned. Detroit Style Pizza is being served up in uber hip places in Brooklyn. The big chains are in on it. And we’re giving Chicago a run. We trace the history of the various players as Guerra’s creation morphed with the times.  Interviews with Wes Pikula, Steve Dolinsky, Marie...

It was horrific, even by the low standards of the urban drug trade. Three dead bodies found in a van on Detroit's east side one night in 1979. All three had been decapitated. We explore the street politics that led to the massacre. And we tell the story of Frank "Nitti" Usher, a crime lord of the era. Former Detroit Free Press reporter Joe Swickard says people were forced to pay attention to details of the crime, as "this was just too much, and I think a triple beheading and bodies found...

The beginnings of Detroit are inaccurately pinned to the arrival of Cadillac on these shores in 1701, but there were various Native American tribes in the area for centuries before that. Thousands of years ago, people came over on a land bridge from Siberia to Alaska. The earliest indigenous people around Detroit were suspected to have come here for sturgeon in the Detroit river. They even left something that is still around to this day: a burial mound at Fort Wayne, on Detroit's southwest...

Smack in the middle of the Civil War, Detroit experienced a riot that was characterized as "the most brutal and bloody riot that ever disgraced any community." A local bar owner, Thomas Faulkner, who was thought to be African-American (he wasn't) went to trial in March, 1863 on sexual assault charges. The accuser was a 10-year-old white girl who later recanted her story. A riot broke out as Faulkner was being escorted to the jail house following his conviction. Two people died. It also set...

On a cold winter day in 1932, in the depths of the Great Depression, some 3,000 or more people met at a park on Detroit's southwest side. They hoped to march to Ford Motor Company's Rouge Plant to present a list of demands to Henry Ford. By modern day standards, those demands weren't all that extravagant. A few demands they asked for: the right to organize, an eight hour day, and a couple of 15 minute breaks on the assembly line. Dearborn police and Ford security met the group at the...

Joe Louis may have been the most famous person to come out of Detroit. He arrived here in the mid-1920s as part of the Great Migration, that influx of African-Americans who came north to escape the Jim Crow South. When he took up boxing as a teenager, there was no stopping him. He became heavyweight boxing champion of the world for 12 years, from 1937 until 1949. His bout against Max Schmeling, not long before World War II, had Louis carrying the entire weight of the free world on his...

Jeff Montgomery was a born activist who played an important role in saving Orchestra Hall. When a hate crime brought tragedy to his personal life, he channeled his talent and drive to working on behalf of the LBGTQ+ community. His stellar career and sad decline are documented in America You Kill Me, which lost its major debut to COVID, but is set to premiere next spring.

Between 1955 & 1974, a nuclear war with the Soviet Union seemed like a possibility. We armed ourselves by placing Nike Missiles around major cities across the U.S. -- including 16 in and around metro Detroit. Six of them, including one on Belle Isle, were outfitted with nuclear warheads. A nuke on Belle Isle? We hear from historians Mel Small, Christopher Bright, William Worden, Jerry Perry; political scientist Ron Stockton; and a cast of historic characters including Winston Churchill...

Hank Greenberg, who entered the Hall of Fame as one of the greatest hitters in the game's history, was the first Jewish star in team sports. He interrupted his baseball career to serve longer in World War II than any other major league player, and led the Tigers to World Series championships before and after the war. We hear from an eclectic cast about his career including poet John Sinclair, sportscaster Eli Zaret, historian Bill Dow, and -- we're not making this up -- Groucho Marx and Bing...

In 1965, consumer advocate Ralph Nader released the book "Unsafe At Any Speed." General Motors wanted to know what Nader was about, sent investigators on his trail, and was caught. General Motors Chairman James Roche apologized on the floor of Congress, which was followed by the National Traffic and Motor Vehicle Safety Act. We follow the trail with veteran auto writer Dave Smith, and Kenneth Whyte, author of the book, "The Sack of Detroit: General Motors and the End of American Enterprise."

Barely two months after the attack on Pearl Harbor, some 120,000 Japanese Americans were ordered into internment camps. When the camps were finally emptied out after the war, some 1,000 came to Detroit. We talk with the curators of the Detroit Historical Museum's Exiled To Motown Exhibit. Scholar Frank Abe tells the story of John Okada, who came here to work at the Detroit Public Library while writing No-No Boy, considered by many to be the great American novel about the event. 

James Vernor invented his ginger ale in downtown Detroit just after the Civil War. More than 15 decades later, we're still fans. The Detroit History Podcast tells the story of this enduringly popular soft drink. You thought Vernor Highway in southwest Detroit was named after the drink? Actually (spoiler alert), it was his work in City Hall. We explain, with help from Keith Wunderlich and Amy Elliott Bragg.

For decades, segregation forced African-Americans migrating from the South to Detroit into one neighborhood: "Black "Bottom," an area just east of downtown, which is now Lafayette Park. Urban renewal plowed the neighborhood under in the 1950s, destroying what had been a thriving place that gave the world Joe Louis and Coleman Young. But the memory of the place never died. A historical marker marking the location, dedicated late this summer, now stands in one of the small parks.

Waiter, is there a ghost in my soup? The Whitney, one of Detroit's great restaurants, began life as a grand 19th Century mansion. David Whitney, one of Michigan's richest lumber barons, would be startled to learn not only that the public is dining on Faroe Island salmon and shrimp and scallop sauté in his Woodward Avenue manor, but tales of paranormal activity have long been a popular menu item. We explore the subtext of "spirits" served at the Whitney.

With the auto industry booming and with Detroit’s population surging in the 1920s, we needed a way to get people and car parts back and forth between Detroit and Windsor. The solution: dig a massive trench beneath the Detroit River current, drop massive concrete tubes into the trench, and drain 'them. What could possibly go wrong? The Detroit History Podcast story of that civil engineering achievement includes an audio bonus: on a quiet night, you can hear freighters passing overhead.

The low-budget, upstart and, to some, shocking dance show on a pioneering African-American-owned TV station put a screenful of Detroit teenagers on the air every day. If you were of an age in the 1970s and 1980s, you watched. Today's Detroit History Podcast gives the back story of a most unlikely -- and important -- piece of the city's cultural history. We talk with show host Nat Morris, former Detroit News TV writer Jim McFarlin, and television producer Tony Mottley.

With a terrible virus sweeping the nation, the word "vaccine" dominated headlines. Not COVID-19, but polio. Not now, but the 1950s.. Many have forgotten, if they ever knew, that Detroit suffered a polio epidemic three years after Dr. Jonas Salk's "miracle drug" quelled America's fear of a crippling disease. We talk with Dr. Peter Salk, Jonah Salk's son, about the creation of the vaccine. We also talk with Dr. Terri Laws about the 1958 polio outbreak in Detroit and the racial disparities that...

Some look at Detroit today and wonder how the abandoned buildings got here. What happened between The Arsenal of Democracy and now? How did a city of nearly 2 million people dwindle down to around 650,000? There are people that blame the 1967 rebellion for the urban decay the city has seen, others blame longtime mayor Coleman Young. In our Season 3 Finale, we explain and debunk these notions. We talk with Thomas Sugrue, author of “The Origins of the Urban Crisis,” and Wayne State University...

Burlesque legend Lottie Graves-Claiborne wowed 'em on several continents, sharing the stage with numerous worldwide stars. But throughout her celebrated 90 years, Lottie insisted on highlighting the art of the tease. This week's Detroit History Podcast focuses on a long life well-lived, and how Lottie the Body's discretion painted a fine line between exotic dancing and mere titillating display.

A historic cafe has morphed its way through generations of change, and still ... still ... there is the feather bowling. Feather bowling? Yes, feather bowling. One man, born in Detroit, found an important piece of his identity playing this unusual game of his forebears on the court at the Cadieux Cafe and he is an important reason the game appears secure in its Detroit home.