During the lull in persecution following the Conference of Carnuntum, the Meletian Schism breaks out in Egypt, while in Palestine controversy erupts over the theology of Origen of Alexandria. Nevertheless the Great Persecution is soon resumed as the Fifth Edict is issued in order to revitalize paganism and marginalize Christians from society. However, just as Galerius prepares to celebrate his Vicennalia, he is struck by a horrific disease, eventually leading him to reconsider his persecution of Christians.