In this episode, we dive into a very important healthcare topic: how collaborations with patients, clinicians and professional medical societies can help us generate evidence from observational data to advance cancer care. We discuss the joint EHDEN / PIONEER / OHDSI study-a-thon about prostate cancer earlier this year with our guest, James N'Dow, Adjunct Secretary General for Education at European Association of Urology and Professor of Urology at the University of Aberdeen, Scotland, and also PIONEER Academic Coordinator. We also touch upon the relationship between RCTs (Randomised Controlled Trials), observational studies, real-world outcomes and how important they are to inform clinical guidelines and improving the quality and experience of cancer care for patients.