Norm, Shaun and Terence are joined by fellow medical student Natalie, who has a PhD in immunology, to discuss innate and adaptive immunity. Natalie studied the regulation of the innate immune system in preterm neonates, focusing on toll-like receptors and how their expression can regulate the transcription of various genes associated with inflammation.  Shout-out to Ben Earner!  Content covered in this episode includes:  - The first line of defense: physical and chemical barriers  - Key cells and proteins associated with the innate immune response such as neutrophils, macrophages, complement, cytokines, etc - Acute vs chronic inflammatory responses  - MHC classes 1 vs 2 - The initiation of the adaptive immune response  - B and T cell structure and function --- Send in a voice message: https://podcasters.spotify.com/pod/show/shaun--norm-and-terence/message