1.8: Pharmacokinetics and Pharmacology of the Autonomic Nervous System (ft. Claire)
Description
The lads are joined by pharmacist (and pharmacology expert) Claire to discuss how drugs go through our bodies and how certain substances can alter or maintain the balance in our autonomic nervous systems! (Trigger warning: mentions suicide.)
Shout-out to Ben Earner!
Things covered in this episode include:
- The potential dangers of grapefruit juice in altering the metabolism of medications
- An overview of pharmacokinetics (absorption, distribution, metabolism and excretion of drugs)
- Core concepts of pharmacogenomics, drug-drug-interactions and toxicology
- ANS pharmacology core concepts (sympathetic vs parasympathetic nervous systems)
- Adrenergic receptor agonists & antagonists, their effects and clinical uses
- Cholinergic receptor agonists & antagonists, their effects and clinical uses
- Acetylcholinesterase inhibitors, their effects and clinical uses
- How amphetamines work
- Some of the drugs covered: adrenaline, noradrenaline, phenylephrine, salbutamol, propranolol, metoprolol, pilocarpine, atropine, tiotropium, amphetamines, pseudoephedrine, neostigmine
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