Guest episode: In this episode we introduce you to a part of our bodies that was invisible to Western scientists until about five years ago; it’s called "the interstitium," a vast network of fluid channels inside the tissues around our organs that scientists have just begun to see, name, and understand. Along the way we look at how new technologies rub up against long-standing beliefs, and how millions of scientists and doctors failed to see what was right in front (and inside!) of their...

You asked, and we’re answering—again! Ask Gastropod returns to answer some of our listeners’ most pressing culinary queries: how did elaborate, expensive cakes become the standard dessert for weddings? Did the deep fried cornmeal blobs known as “hush puppies” get their name from Confederate soldiers or racist stories from the plantation-era South? And could a trendy "new" variety of milk (that's actually ancient) allow the dairy-intolerant to snarf down cheese and ice cream without digestive...

It's not your imagination, food allergies are really on the rise. One recent study found that severe allergic reactions to food have increased by more than 300 percent over the past decade. And they don't just affect Americans or kids—they're on the rise in adults around the world. Even pets are getting food allergies. So what's going on? Why would your body decide that food—something that's actually essential to keeping you alive—needs to be attacked like a dangerous invader? And why would...

Today, it’s a breakfast staple, but, as recently as 1960, The New York Times had to define it for readers—as “an unsweetened doughnut with rigor mortis.” That’s right, this episode is all about the bagel, that shiny, ring-shaped, surprisingly dense bread that makes the perfect platform for cream cheese and lox. Where did it come from? Can you get a decent bagel outside New York City? And what does it have in common with the folding ping-pong table? Come get your hot, fresh bagel science and...

For as long as we’ve been making Gastropod, co-host Nicky has also been working on another project: writing a book all about refrigeration. Well, time to pop the champagne you’ve had stashed in the icebox, because that book comes out June 25—and we’re giving Gastropod listeners an exclusive preview! This episode, Cynthia and Nicky talk about how a high school dropout's get-rich-quick scheme, some deadly explosions, and lots and lots of beer brought us the humming boxes of cold now ubiquitous...

Based on all the hype, you'd be forgiven for believing that the fish oils known as omega-3s are the solution to every problem. Heart disease, dementia, depression, even obesity—the list of ailments that experts claim a daily dose of omega-3 can help prevent seems endless. And with more than ten percent of Americans taking a capsule of fish oil daily, omega-3s are one of the most profitable supplements in the world, too. Listen in this episode, as author Paul Greenberg and scientist JoAnn...

Your pantry's sweetest ingredient has an extremely bitter history. The sap-producing grass known as sugarcane has been grown and enjoyed by humans for at least 10,000 years, but it was only relatively recently that it went from a luxury to an everyday ingredient—a change that also triggered genocide, slavery, and the invention of modern racism. In this episode, how the Crusades got Europeans addicted to the sweet stuff, and how that appetite deforested southern Europe and kicked off the trade...

From our friends at Switched on Pop: Where were you when you learned that the McDonald's jingle "I'm lovin' it" was originally part of a full-fledged pop song by Justin Timberlake and Pharrell that flopped on the charts but found staying power as a slogan? For us, it was recording our live episode about sponsored content in pop back in March 2024, and we have not been the same since. Shaken by this revelation, we found ourselves asking, "What else don't we know about fast food jingles?" Turns...

When you go out for a meal, it’s not just what's on your plate that matters, it's what's in your eardrums, too. From dining rooms so loud you have to shout to be heard, to playlists that sound like a generic Millennial Spotify account, it's not surprising that sound is the single most complained about aspect of restaurants. This episode, Gastropod explores the science behind the sonic experience of eating. Are restaurants really getting louder, and, if so, why? What does it take to create the...

You've probably never heard of David Fairchild. But if you've savored kale, mango, peaches, dates, grapes, a Meyer lemon, or a glass of craft beer lately, you've tasted the fruits of his globe-trotting travels in search of the world's best crops—and his struggles to get them back home to the United States. This episode, we talk to Daniel Stone, author of The Food Explorer, a new book all about Fairchild's adventures. Listen in now for tales of pirates and biopiracy, eccentric patrons and...

In his day, Luther Burbank was a horticultural rock star: everyone from opera singers to movie stars and European royalty to an Indian guru traveled to Santa Rosa, California, to meet him. Dubbed the "plant wizard," Burbank invented the plumcot and the stoneless plum, the white blackberry, and the potato variety used in every French fry you've ever eaten—as well as some 800 more new-and-improved plants, from walnuts to rhubarb. His fame as a plant inventor put him in the same league as Thomas...

Americans eat more shrimp than any other seafood: on average, each person in the US gobbles up close to six pounds of the cheap crustaceans every year. We can eat so many of these bug-like shellfish because they’re incredibly inexpensive, making them the stars of all-you-can-eat shrimp buffets and single-digit seafood deals. But we've got bad news: this is one bargain that's too good to be true. More than 90 percent of the shrimp we eat comes from overseas, where looser regulations lead to...

If we at Gastropod were asked to name a perfect food, the oyster would be at the top of our list. Oysters are pretty much always our answer to the question of what we'd like to eat this evening—but are they also the answer to the slow-motion disaster of disappearing coastlines worldwide? Join us this episode as we discover how this magical mollusk contains a pearl of hope in the fight to counter rising sea-levels, prevent erosion, and buffer storm surges everywhere from hurricane-hit New...

This episode, we've got the exclusive on the preliminary results of the world's largest personalized nutrition experiment. Genetic epidemiologist Tim Spector launched the study, called PREDICT, to answer a simple but important question: do we each respond to different foods differently? And, if so, why? How much of that difference is genetic, how much is due to gut microbes, and how much is due to any one of the dozens of other factors that scientists think affect our metabolic processes?...

If "Cajun-style" only makes you think of spicy chicken sandwiches and popcorn shrimp, you need to join us in the Big Easy this episode, to meet the real Cajun flavor. Cajun cuisine and its close cousin, Creole, were born out of the unique landscape of the Mississippi River delta, whose bounty was sufficient to support large, complex Indigenous societies, without the need for farming or even social hierarchies, for thousands of years. Europeans were slow to appreciate the wealth of this...

After Dan’s pasta shape, cascatelli, was launched, people everywhere were cooking with it and sending him photos of what they were making. As exciting as that was, he was disappointed that most folks were only making a handful of well-worn dishes with this new shape. So Dan decided to write a cookbook to show the world that there’s so much more you can and should be putting on all your pasta shapes, cascatelli and beyond! There’s only one problem: he’s never written a recipe in his life. In...

Close your eyes and imagine this: a world without stuffed crust pizza. We know!—but that was the dismal state of the Italian flatbread scene before 1985, when Anthony Mongiello, aka The Big Cheese, came up with an innovation that loaded even more cheese onto pizza, while saving crusts nationwide from the trashcan. It was a multi-million dollar idea, Mongiello was sure—if only he could figure out how to protect his intellectual property and license it. But can you copyright the recipe for...

Shoestring, waffle, curly, or thick-cut: however you slice it, nearly everyone loves a deep-fried, golden brown piece of potato. But that's where the agreement ends and the battles begin. While Americans call their fries "French," Belgians claim that they, not the French, invented the perfect fry. Who's right? This episode, we take you right into the heart of the battle that continues to be waged over who owns the fry—who invented it, who perfected it, who loves it the most? And then we take...

In contrast to the abundance of the Arctic, in Antarctica, "once you leave the coast, you're basically heading to the moon." Jason Anthony, who spent several summers on the seventh continent, told us that in this desert of ice and stone (where the largest terrestrial animal is a tiny wingless midge), food isn't just important—it's everything. This episode is packed full of stories of survival at Earth's southernmost points, from Heroic Era expedition chefs whipping up croissants on the ice,...

You may feel like it's cold where you live, but in the Arctic, the average temperature is well below freezing all year round. In winter, it's also pitch black for weeks on end—not an ideal environment for growing food. Still, for thousands of years, people in the Arctic have thrived in a landscape that most outsiders would find fatally inhospitable. This episode, we point our compasses north on a journey to discover how traditional knowledge, ingenuity, and a lot of hard work—combined with...

“There’s the faintest soupçon of asparagus and just a flutter of Edam cheese,” says Paul Giamatti in the movie Sideways. Believe it or not, he's describing pinot noir, not quiche. The world of sommeliers, wine lists, and tasting notes is filled with this kind of language, prices seemingly rising in step with the number of bizarre adjectives. It's tempting to dismiss the whole thing as B.S., but listen in: this episode, author Bianca Bosker takes us along on her journey into the history and...

This week, Gastropod tells the story of two countries and their shared obsession with a plant: Camellia sinensis, otherwise known as the tea bush. The Chinese domesticated tea over thousands of years, but they lost their near monopoly on international trade when a Scottish botanist, disguised as a Chinese nobleman, smuggled it out of China in the 1800s, in order to secure Britain's favorite beverage and prop up its empire for another century. The story involves pirates, ponytails, and hard...

When it comes to booze, it’s fun to be bitter: an Aperol spritz has been the drink of summer for about five years, vermouth and soda was apparentlythe "hot girl" drink of 2023, and amaro is having "a major moment." Bitter botanical beverages are everywhere, but that doesn’t mean we understand what on earth they are. Could you explain the difference between vermouth and amaro, or whether either is an aperitif or a digestif? Where do Aperol, Campari, and Chartreuse fit in, and what’s the...

Though rice might not feature in a hit 1990s Vanilla Ice rap, this grain tops the charts in other ways: it's the staple food for more than half the global population, and it's grown by more farmers than any other crop on Earth, from Japan to West Africa to Italy's Po River valley. Rice is so central that it's been used as currency, embedded itself in language, and formed the basis of beloved dishes, from sushi to jollof to risotto. But this adaptable grass has two features that have molded...