Join us as we recap various topics discussed throughout the year, including hormonal and non-hormonal therapy for menopause symptoms, hemochromatosis, evaluation and management of hematuria, updates in diabetes management (insulin, GLP1 agonists, SGLT2 inhibitors, hypoglycemia), xylazine overdose and withdrawal, primary aldosteronism, resistant hypertension, delirium, and its implications, the ACORN trial on AKI risk with pip-tazo vs. cefepime, the REPRIEVE trial on statin therapy in patients with HIV, inpatient heart failure management, the implications of kratom use, and the effectiveness of RSV vaccines. Plus, Paul Williams (@PaulNWilliamz), Rahul Ganatra (@rbganatra), Nora Taranto (@norataranto), and Matt Watto (@doctorwatto) share their picks of the year and take a moment to reflect on their gratitude for the fans and the opportunity to work on Curbsiders. Our team needed a break so we did not make CME for this episode.  Show Segments Time Stamps are for Patreon (Ad-Free) Version 00:00 Introduction and Overview 09:42 Hormonal and Non-Hormonal Therapy for Menopause Symptoms 14:20 Understanding Hemochromatosis 19:24 Evaluation and Management of Hematuria 25:00 Updates in Diabetes Management 29:35 Xylazine Overdose and Withdrawal 35:35 Primary Aldosteronism 39:36 Resistant Hypertension 44:12 Delirium and its Implications 46:29 The Acorn trial and AKI risk 49:47 HIV trial: Reprieve 51:11 Updates in hospital medicine 56:00 Kratom and its implications 59:11 RSV vaccines and their effectiveness 01:05:38 Reflections and Gratitude Credits Written, Produced, and Hosted by: Nora Taranto MD, Rahul Ganatra MD, MPH; Matthew Watto MD, FACP; Paul Williams MD, FACP Cover Art: Matthew Watto MD, FACP Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP Technical Production: PodPaste Sponsor - Glass Health Glass Health was founded in 2021 and has the mission of empowering doctors with AI-powered clinical decision support.  Glass helps clinicians to draft differential diagnoses and draft clinical plans using physician-validated context.  You can also use Glass to capture knowledge of all the schemas, scripts, cases, and pearls that you encounter and leverage them to take better care of patients.  Try Glass for yourself by visiting https://glass.health Personal knowledge management features are completely free and with Glass Pro, you get access to their powerful AI.  You can get one month of Glass Pro free by signing up at https://glass.health and using the code CURBSIDERS  Glass, like a clinical reference text or podcast, should never replace clinician judgment.