What if I told you that 80% of your health in old age is up to you, how you live your life. Your body and brain have inbuilt defence systems against ageing, called “longevity genes” - armed forces that that fight against disease, stress, and ageing. Research is starting to work out the diet and lifestyle that most effectively turn on these sirtuin genes in humans, which have the potential to reverse ageing.  I distill what we know about how to activate these genes to live longer and reverse ageing into five simple steps that can almost anyone can do. RESOURCES: Discover your risk of developing dementia Watch Better Brain, Better You Lu et al. (2020) Reprogramming to recover youthful epigenetic information and restore vision. Nature 588, 124-129 Kane, & Sinclair, D.A. (2019) Epigenetic changes during aging and their reprogramming potential. Critical Reviews of Biochemical Molecular Biology 54, 61-83. Sinclair, DA & Laplante, MD, (2019) Lifespan: Why We Age - And Why We Don't Have to Harper Collins