Welcome to the Siim Land podcast. I’m your host Siim Land and our guest today is Matt Kaeberlein. Matt is a Phd and researcher in the biology of aging. He’s one of the world’s most renown names in longevity, life extension and healthy aging. Head over to biohackercenter.com and use the code SIIMLAND for a 10% discount. Timestamps: 01:00 Changes in Aging Research Over the Past Decades 05:00 Is Aging a Modifiable Program 08:45 How Long Can Humans Live 11:13 Genetic Engineering for Longevity 13:03 Why Do Some People Live Over 100 18:20 Lifestyle Factors That Extend Lifespan 24:10 Calorie Restriction for Living Longer 28:22 Prolonged Calorie Restriction in Humans 30:39 Food Quality and Calorie Restriction Diet 34:05 Intermittent Fasting and Time Restricted Eating 40:12 Calorie Restriction Mimetics 43:00 Rapamycin Research 50:30 Dog Rapamycin Study 54:05 Are Biological Age Tests Accurate 01:02:40 Is Age Reversal Possible 01:11:25 Risk of Low Protein Diets